Evidence map›Paper›PMID 31635058›Full record

ArticleGenes2019

Frameshift Variant in MFSD12 Explains the Mushroom Coat Color Dilution in Shetland Ponies.

Jocelyn Tanaka, Tosso Leeb, James Rushton, Thomas R Famula, Maura Mack, Vidhya Jagannathan, Christine Flury, Iris Bachmann, John Eberth, Sue M McDonnell and 2 more

Open access · goldAbstract read
In one paragraph

Article in Genes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 19 citations in OpenAlex.

  1. Lysosomal reduced thiols are essential for mouse embryonic development.Proceedings of the National Academy of Sciences of the United States of America · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 3 countries.

Jocelyn TanakaVeterinary Genetics Laboratory, School of Veterinary Medicine, University of California, Davis, CA 95616, USA. jltanaka@ucdavis.edu.ORCID 0000-0002-4512-6235
Tosso LeebInstitute of Genetics, University of Bern, 3001 Bern, Switzerland. tosso.leeb@vetsuisse.unibe.ch.ORCID 0000-0003-0553-4880
James RushtonRowe Equine Ltd, Wotton Under Edge, GLOS GL12 7PP, UK. jamesrushton@rowevetgroup.com.
Thomas R FamulaDepartment of Animal Science, University of California, One Shields Ave, Davis, CA 95616, USA. trfamula@ucdavis.edu.
Maura MackVeterinary Genetics Laboratory, School of Veterinary Medicine, University of California, Davis, CA 95616, USA. Maura.Mack@colostate.edu.
Vidhya JagannathanInstitute of Genetics, University of Bern, 3001 Bern, Switzerland. vidhya.jagannathan@vetsuisse.unibe.ch.ORCID 0000-0002-8155-0041
Christine FlurySchool of Agricultural Forest and Food Sciences, Bern University of Applied Sciences, 3052 Zollikofen, Switzerland. christine.flury@bfh.ch.
Iris BachmannAgroscope, Swiss National Stud Farm, 1580 Avenches, Switzerland. iris.bachmann@agroscope.admin.ch.
John EberthCollege of Agriculture, Food and Environment, University of Kentucky, Lexington, KY 40546, USA. john.eberth@uky.edu.
Sue M McDonnellHavemeyer Equine Behavior Program, University of Pennsylvania School of Veterinary Medicine, New Bolton Center Department of Clinical Studies, Kennett Square, PA 19348, USA. suemcd@vet.upenn.edu.
Maria Cecilia T PenedoVeterinary Genetics Laboratory, School of Veterinary Medicine, University of California, Davis, CA 95616, USA. mctorrespenedo@ucdavis.edu.
Rebecca R BelloneVeterinary Genetics Laboratory, School of Veterinary Medicine, University of California, Davis, CA 95616, USA. rbellone@ucdavis.edu.ORCID 0000-0001-8838-7227
University of California, Davis · USUniversity of Bern · CHAgroscope · CHBern University of Applied Sciences · CHRenishaw (United Kingdom) · GBUniversity of Kentucky · USUniversity of Pennsylvania · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mushroom is a unique coat color phenotype in Shetland Ponies characterized by the dilution of the chestnut coat color to a sepia tone and is hypothesized to be a recessive trait. A genome wide association study (GWAS), utilizing the Affymetrix 670K array (MNEc670k) and a single locus mixed linear model analysis (EMMAX), identified a locus on ECA7 for further investigation (

Indexed as

Frameshift MutationAnimal FurAnimalsHorsesMembrane Transport ProteinsPigmentationMembrane Transport Proteinscoat colordilutionEquus caballusMFSD12pigmentation

Identifiers

PMID31635058
PMCPMC6827053
OpenAlexW2980420848

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.