Evidence map›Paper›PMID 31634243›Full record

ArticleChinese medical journal2019

Clinical efficacy of 595-nm pulsed-dye laser in treatment of childhood facial spider nevi: a retrospective study of 110 patients.

Cheng Zhang, Hong-Song Ge, Sen Yang, Xue-Jun Zhang

Abstract read
In one paragraph

Article in Chinese medical journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Pulsed Dye Laser for Port Wine Stains in 974 Children: A 20-Year Study in China.Clinical, cosmetic and investigational dermatology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Cheng ZhangDepartment of Dermatology, The First Affiliated Hospital of Anhui Medical University, The Key Laboratory of Dermatology (Anhui Medical University), Ministry of Education, The Key Laboratory of Major Autoimmune Diseases, Hefei, Anhui 230022, China.
Hong-Song GeDepartment of Dermatology, Anhui Provincial Children's Hospital, Hefei, Anhui 230051, China.
Sen YangDepartment of Dermatology, The First Affiliated Hospital of Anhui Medical University, The Key Laboratory of Dermatology (Anhui Medical University), Ministry of Education, The Key Laboratory of Major Autoimmune Diseases, Hefei, Anhui 230022, China.
Xue-Jun ZhangDepartment of Dermatology, The First Affiliated Hospital of Anhui Medical University, The Key Laboratory of Dermatology (Anhui Medical University), Ministry of Education, The Key Laboratory of Major Autoimmune Diseases, Hefei, Anhui 230022, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSpider nevi (SN) are quite common in children. SN are treated via different techniques, and complete removal often requires multiple treatments. However, few studies have evaluated the treatment of SN. The present study aimed to evaluate the therapeutic effect and safety of a 595-nm pulsed-dye laser (PDL) for treating facial SN in children.

methodsA total of 110 children aged 0.2 to 12 years with facial SN were treated with a 595-nm PDL in a single institution from January 2016 to February 2018. In accordance with the treatment method, the patients were retrospectively divided into the small-spot-combined-with-large-spot group (SL-group) and the large-spot group (L-group). Patients with poor therapeutic results were re-treated every 6 weeks until the lesions disappeared. The minimum follow-up period was 1 year. The groups were compared using independent-samples t tests, Mann-Whitney U test, Chi-square test, and Fisher exact probability test.

resultsThe therapeutic efficacy was significantly higher in the SL-group than in the L-group, with clearance rates of 90.9% and 53.0% after the primary treatment, respectively (χ = 17.937, P < 0.001). For skin lesions with a central spider body diameter ≥1 mm, the once-treatment cure rates were 100% in the SL-group and 34.8% in the L-group (χ = 20.780, P < 0.001). For skin lesions with a central spider body diameter <1 mm, the once-treatment cure rates were 82.6% in the SL-group and 62.8% in the L-group (χ = 3.961, P = 0.138). The rates of adverse reactions and recurrence did not differ between the two groups (P = 0.141 and P = 1.000, respectively).

conclusionsThe 595-nm PDL might be a safe and effective treatment option for facial SN in children. The small-spot-combined-with-large-spot method is especially suitable for SN with a central spider body diameter ≥1 mm.

Indexed as

ChildChild, PreschoolFaceFemaleHumansInfantLasers, DyeMaleRecurrenceRetrospective StudiesSkinTelangiectasis

Identifiers

PMID31634243
PMCPMC6831075

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.