Evidence map›Paper›PMID 31634023›Full record

Trial reportJournal of aerosol medicine and pulmonary drug delivery2020

Clinical Bioequivalence of Wixela Inhub and Advair Diskus in Adults With Asthma.

Dik Ng, Edward M Kerwin, Martha V White, S David Miller, Scott Haughie, Jonathan K Ward, Richard Allan

Registry-linked trialOpen access · hybridAbstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in Journal of aerosol medicine and pulmonary drug delivery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02245672 (A Randomized, Double-blind, Double Dummy, Parallel Group Study to Determine the Local Equivalence of Multiple Doses of MGR001 to Advair Diskus Administered Via Oral Inhalation in Adult Asthma Patients), which is not on this map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02245672 phase3completednot on this map

A Randomized, Double-blind, Double Dummy, Parallel Group Study to Determine the Local Equivalence of Multiple Doses of MGR001 to Advair Diskus Administered Via Oral Inhalation in Adult Asthma Patients

TypeinterventionalSponsorMylan Pharma UK Ltd.Ran2014 to 2015Enrolled1,128ConditionsAsthmaArmsMGR001 (Fixed dose combination of Fluticasone propionate and salmeterol xinafoate), Advair (Fixed dose combination of Fluticasone propionate and salmeterol xinafoate), Placebo
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Review
  5. Article
  6. Journal of aerosol medicine and pulmonary drug delivery · 2022
    Article
  7. Review
  8. Review
  9. Wixela Inhub: Dosing PerformanceJournal of aerosol medicine and pulmonary drug delivery · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Dik NgMylan Pharma UK Ltd., Sandwich, Kent, United Kingdom.
Edward M KerwinClinical Research Institute of Southern Oregon, Medford, Oregon.
Martha V WhiteInstitute for Asthma and Allergy, Wheaton, Maryland.
S David MillerNortheast Medical Research Associates, Inc., North Dartmouth, Massachusetts.
Scott HaughieMylan Pharma UK Ltd., Sandwich, Kent, United Kingdom.
Jonathan K WardMylan Pharma UK Ltd., Sandwich, Kent, United Kingdom.
Richard AllanMylan Pharma UK Ltd., Sandwich, Kent, United Kingdom.
Pfizer (United Kingdom) · GBClinical Research Institute · USInstitute for Asthma and Allergy · USMedical Research Associates · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Administration, InhalationAdolescentAdultAgedAged, 80 and overArea Under CurveAsthmaBronchodilator AgentsDouble-Blind MethodDry Powder InhalersFemaleFluticasone-Salmeterol Drug CombinationForced Expiratory VolumeHumansLungMaleBronchodilator AgentsFluticasone-Salmeterol Drug CombinationAdvair Diskusfluticasone propionategeneric drugslocal bioequivalencesalmeterolWixela Inhub

Identifiers

PMID31634023
PMCPMC7133441
OpenAlexW2981742323

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.