Evidence map›Paper›PMID 31633808›Full record

ArticleJournal of the American Geriatrics Society2020

Racial Differences in Elevated C-Reactive Protein Among US Older Adults.

Heather R Farmer, Linda A Wray, Ying Xian, Hanzhang Xu, Neha Pagidipati, Eric D Peterson, Matthew E Dupre

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Geriatrics Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 35 citations in OpenAlex.

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  8. Chemotherapy-induced peripheral neuropathy in breast cancer: a narrative review.Translational breast cancer research : a journal focusing on translational research in breast cancer · 2026
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  13. Stress-responsive biomarkers and sexual behaviors among young women in rural South Africa.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Heather R FarmerDepartment of Population Health Sciences, Duke University, Durham, North Carolina.ORCID 0000-0003-3889-548X
Linda A WrayDepartment of Biobehavioral Health, The Pennsylvania State University, University Park, Pennsylvania.
Ying XianDuke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina.ORCID 0000-0002-1237-1162
Hanzhang XuDepartment of Family Medicine and Community Health, Duke University Medical Center, Durham, North Carolina.ORCID 0000-0001-9617-247X
Neha PagidipatiDuke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina.
Eric D PetersonDuke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina.
Matthew E DupreDepartment of Population Health Sciences, Duke University, Durham, North Carolina.ORCID 0000-0002-0976-4715
Duke University · USPennsylvania State University · US

Funding

BEHAVIOR AND PHYSIOLOGY IN AGINGT32AG000029 · NIA · DUKE UNIVERSITY · PI Maria Marquine · 1985 to 2026
$9.3M
NIA NIH HHS T32 AG000029
6 · The paper itself

Abstract

objectivesTo investigate racial differences in elevated C-reactive protein (CRP) and the potential factors contributing to these differences in US older men and women.

designNationally representative cohort study.

settingHealth and Retirement Study, 2006 to 2014.

participantsNoninstitutionalized non-Hispanic black and white older adults living in the United States (n = 13 517). MEASUREMENTS: CRP was categorized as elevated (>3.0 mg/L) and nonelevated (≤3.0 mg/L) as the primary outcome. Measures for demographic background, socioeconomic status, psychosocial factors, health behaviors, and physiological health were examined as potential factors contributing to race differences in elevated CRP.

resultsMedian CRP levels (interquartile range) were 1.67 (3.03) mg/L in whites and 2.62 (4.95) mg/L in blacks. Results from random effects logistic regression models showed that blacks had significantly greater odds of elevated CRP than whites (odds ratio = 2.58; 95% confidence interval [CI] = 2.20-3.02). Results also showed that racial difference in elevated CRP varied significantly by sex (predicted probability [PP] [white men] = 0.28 [95% CI = 0.27-0.30]; PP [black men] = 0.38 [95% CI = 0.35-0.41]; PP [white women] = 0.35 [95% CI = 0.34-0.36]; PP [black women] = 0.49 [95% CI = 0.47-0.52]) and remained significant after risk adjustment. In men, the racial differences in elevated CRP were attributable to a combination of socioeconomic (12.3%) and behavioral (16.5%) factors. In women, the racial differences in elevated CRP were primarily attributable to physiological factors (40.0%).

conclusionIn the US older adult population, blacks were significantly more likely to have elevated CRP than whites; and the factors contributing to these differences varied in men and women. J Am Geriatr Soc 68:362-369, 2020.

Indexed as

AgedBlack or African AmericanC-Reactive ProteinFemaleHumansMaleMiddle AgedProspective StudiesRace FactorsSex DistributionSocioeconomic FactorsUnited StatesWhite PeopleC-Reactive ProteinC-reactive proteinHealth and Retirement Studyrace

Identifiers

PMID31633808
PMCPMC8211020
OpenAlexW2981892826

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.