Evidence map›Paper›PMID 31633786›Full record

ArticleMolecular biology and evolution2020

Treeio: An R Package for Phylogenetic Tree Input and Output with Richly Annotated and Associated Data.

Li-Gen Wang, Tommy Tsan-Yuk Lam, Shuangbin Xu, Zehan Dai, Lang Zhou, Tingze Feng, Pingfan Guo, Casey W Dunn, Bradley R Jones, Tyler Bradley and 4 more

Abstract read
In one paragraph

Article in Molecular biology and evolution, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 351 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
351citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

351 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Global epidemiology of tick-borneFrontiers in cellular and infection microbiology · 2026
    Pooled it
  2. Meta-Analysis of the Gut Microbiome: An African American Representation.International journal of environmental research and public health · 2025
    Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Identification of a candidate self-incompatibility locus in beet (Beta vulgaris).TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Lifestyles ofProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  19. Article
  20. Article

291 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Li-Gen WangDepartment of Bioinformatics, School of Basic Medical Sciences, Southern Medical University, Guangzhou, Guangdong, China.
Tommy Tsan-Yuk LamState Key Laboratory of Emerging Infectious Disease and Centre of Influenza Research, School of Public Health, The University of Hong Kong, Hong Kong SAR, China.
Shuangbin XuDepartment of Bioinformatics, School of Basic Medical Sciences, Southern Medical University, Guangzhou, Guangdong, China.
Zehan DaiDepartment of Bioinformatics, School of Basic Medical Sciences, Southern Medical University, Guangzhou, Guangdong, China.
Lang ZhouDepartment of Bioinformatics, School of Basic Medical Sciences, Southern Medical University, Guangzhou, Guangdong, China.
Tingze FengDepartment of Bioinformatics, School of Basic Medical Sciences, Southern Medical University, Guangzhou, Guangdong, China.
Pingfan GuoDepartment of Bioinformatics, School of Basic Medical Sciences, Southern Medical University, Guangzhou, Guangdong, China.
Casey W DunnDepartment of Ecology and Evolutionary Biology, Yale University, New Haven, CT.
Bradley R JonesBritish Columbia Centre for Excellence in HIV/AIDS, Vancouver, Canada.
Tyler BradleyCivil, Architectural, and Environmental Engineering, Drexel University, Philadelphia, PA.
Huachen ZhuState Key Laboratory of Emerging Infectious Disease and Centre of Influenza Research, School of Public Health, The University of Hong Kong, Hong Kong SAR, China.
Yi GuanState Key Laboratory of Emerging Infectious Disease and Centre of Influenza Research, School of Public Health, The University of Hong Kong, Hong Kong SAR, China.
Yong JiangGuangdong Provincial Key Laboratory of Proteomics, School of Basic Medical Sciences, Southern Medical University, Guangzhou, Guangdong, China.
Guangchuang YuDepartment of Bioinformatics, School of Basic Medical Sciences, Southern Medical University, Guangzhou, Guangdong, China.

Funding

NIAID NIH HHS HHSN272201400006C
6 · The paper itself

Abstract

Phylogenetic trees and data are often stored in incompatible and inconsistent formats. The outputs of software tools that contain trees with analysis findings are often not compatible with each other, making it hard to integrate the results of different analyses in a comparative study. The treeio package is designed to connect phylogenetic tree input and output. It supports extracting phylogenetic trees as well as the outputs of commonly used analytical software. It can link external data to phylogenies and merge tree data obtained from different sources, enabling analyses of phylogeny-associated data from different disciplines in an evolutionary context. Treeio also supports export of a phylogenetic tree with heterogeneous-associated data to a single tree file, including BEAST compatible NEXUS and jtree formats; these facilitate data sharing as well as file format conversion for downstream analysis. The treeio package is designed to work with the tidytree and ggtree packages. Tree data can be processed using the tidy interface with tidytree and visualized by ggtree. The treeio package is released within the Bioconductor and rOpenSci projects. It is available at https://www.bioconductor.org/packages/treeio/.

Indexed as

Computational BiologyData MiningInternetPhylogenySoftwarebioconductordata integrationggtreephylogeny

Identifiers

PMID31633786
PMCPMC6993851

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.