Evidence map›Paper›PMID 31633611›Full record

ArticleJournal of acquired immune deficiency syndromes (1999)2020

Knowledge of HIV Status Is Associated With a Decrease in the Severity of Depressive Symptoms Among Female Sex Workers in Uganda and Zambia.

Katrina F Ortblad, Daniel Kibuuka Musoke, Michael M Chanda, Thomson Ngabirano, Jennifer Velloza, Jessica E Haberer, Margaret McConnell, Catherine E Oldenburg, Till Bärnighausen

Open access · hybridAbstract read
In one paragraph

Article in Journal of acquired immune deficiency syndromes (1999), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
6.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 4 countries.

Katrina F OrtbladDepartment of Global Health, University of Washington, Seattle, WA.
Daniel Kibuuka MusokeInternational Research Consortium, Kampala, Uganda.
Michael M ChandaJohn Snow, Inc., Lusaka, Zambia.
Thomson NgabiranoUganda Health Marketing Group, Kampala, Uganda.
Jennifer VellozaDepartment of Global Health, University of Washington, Seattle, WA.
Jessica E HabererMassachusetts General Hospital Global Health, Boston, MA.
Margaret McConnellDepartment of Global Health and Population, Harvard T.H. Chan School of Public Health, Boston, MA.
Catherine E OldenburgFrancis I. Proctor Foundation, University of California San Francisco, San Francisco, CA.
Till BärnighausenDepartment of Global Health, University of Washington, Seattle, WA.
University of Washington · USHarvard Global Health Institute · USHeidelberg University · DEMassachusetts General Hospital · USSan Francisco Foundation · USWorld Health Organization - Uganda · UG

Funding

HIV and Other Infectious Consequences of Substance UseT32DA013911 · NIDA · MIRIAM HOSPITAL · PI TRACI C GREEN, JOSIAH D RICH · 2001 to 2026
$9.6M
The Brown Initiative in HIV and AIDS Clinical Research for Minority CommunitiesR25MH083620 · NIMH · MIRIAM HOSPITAL · PI NUNN, AMY STEWART · 2008 to 2025
$3.7M
Integrated PrEP and ART delivered in Ugandan public health clinics to improve HIV and ART outcomes for HIV serodiscordant couplesR01MH110296 · NIMH · UNIVERSITY OF WASHINGTON · PI HEFFRON, RENEE A. · 2017 to 2021
$3.2M
Training Tanzanian Researchers for HIV/AIDS Implementation ScienceD43TW009775 · FIC · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI Wafaie W Fawzi, Christopher Sudfeld · 2015 to 2026
$3.0M
New Methods for the design and evaluation of large HIV prevention interventionsR01AI112339 · NIAID · YALE UNIVERSITY · PI SPIEGELMAN, DONNA L · 2014 to 2017
$2.7M
Causal Pathways to population health impact of HIV antiretroviral treatmentR01HD084233 · NICHD · UNIVERSITY OF KWAZULU-NATAL · PI BARNIGHAUSEN, TILL, TANSER, FRANK COURTENEY · 2015 to 2021
$2.3M
HIV self-testing to improve the efficiency of PrEP deliveryR01MH113572 · NIMH · UNIVERSITY OF WASHINGTON · PI MUGO, NELLY RWAMBA, NGURE, KENNETH · 2018 to 2021
$2.2M
Can HIV Hot-Spots be eradicated? An intervention to decrease HIV transmission to young women in rural KwaZulu-Natal South AfricaR01AI124389 · NIAID · UNIVERSITY OF KWAZULU-NATAL · PI BARNIGHAUSEN, TILL, TANSER, FRANK COURTENEY · 2016 to 2020
$2.1M
Optimizing mHealth for adherence monitoring and interventionK24MH114732 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI HABERER, JESSICA ELIZABETH · 2017 to 2021
$800k
Depression and Pre-Exposure Prophylaxis Use among sub-Saharan African WomenF31MH113420 · NIMH · UNIVERSITY OF WASHINGTON · PI VELLOZA, JENNIFER · 2017 to 2018
$84k
FIC NIH HHS D43 TW009775NIAID NIH HHS R01 AI112339NIAID NIH HHS R01 AI124389NICHD NIH HHS R01 HD084233NIDA NIH HHS T32 DA013911NIMH NIH HHS F31 MH113420NIMH NIH HHS K24 MH114732NIMH NIH HHS R01 MH110296NIMH NIH HHS R01 MH113572NIMH NIH HHS R25 MH083620Wellcome Trust
6 · The paper itself

Abstract

backgroundKnowledge of HIV-positive status may result in depressive symptoms, which may be a concern to scaling novel HIV testing interventions that move testing outside the health system and away from counselor support.

settingUganda and Zambia.

methodsWe used longitudinal data from 2 female sex worker (FSW) cohorts in Uganda (n = 960) and Zambia (n = 965). Over 4 months, participants had ample opportunity to HIV testing using standard-of-care services or self-tests. At baseline and 4 months, we measured participants' perceived knowledge of HIV status, severity of depressive symptoms (continuous PHQ-9 scale, 0-27 points), and prevalence of likely depression (PHQ-9 scores ≥10). We estimated associations using individual fixed-effects estimation.

resultsCompared with unknown HIV status, knowledge of HIV-negative status was significantly associated with a decrease in depressive symptoms of 1.06 points in Uganda (95% CI -1.79 to -0.34) and 1.68 points in Zambia (95% CI -2.70 to -0.62). Knowledge of HIV-positive status was significantly associated with a decrease in depressive symptoms of 1.01 points in Uganda (95% CI -1.82 to -0.20) and 1.98 points in Zambia (95% CI -3.09 to -0.88). The prevalence of likely depression was not associated with knowledge of HIV status in Uganda but was associated with a 14.1% decrease with knowledge of HIV-negative status (95% CI -22.1% to -6.0%) and a 14.3% decrease with knowledge of HIV-positive status (95% CI -23.9% to -4.5%) in Zambia.

conclusionsKnowledge of HIV status, be it positive or negative, was significantly associated with a decrease in depressive symptoms in 2 FSW populations. The expansion of HIV testing programs may have mental health benefits for FSWs.

Indexed as

AdultDepressionFemaleHIV InfectionsHumansLongitudinal StudiesRandomized Controlled Trials as TopicSeverity of Illness IndexSex WorkUgandaZambia

Identifiers

PMID31633611
PMCPMC6898780
OpenAlexW2980380426

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.