Evidence map›Paper›PMID 31633482›Full record

ArticleeLife2019

Daniel P Murphy, Andrew Eo Hughes, Karen A Lawrence, Connie A Myers, Joseph C Corbo

Open access · goldAbstract read
In one paragraph

Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 45 citations in OpenAlex.

  1. Article
  2. Global epigenetic immunohistochemical markers reveal developmental connections of distinct cell types during fetal development.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Article
  3. The molecular evolution of vertebrate organs.Nature ecology & evolution · 2026
    Review
  4. PreclinicalbioRxiv : the preprint server for biology · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Pathogenic variants inGenome research · 2024
    Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Daniel P MurphyDepartment of Pathology and Immunology, Washington University School of Medicine, St. Louis, United States.ORCID 0000-0003-4846-4608
Andrew Eo HughesDepartment of Pathology and Immunology, Washington University School of Medicine, St. Louis, United States.
Karen A LawrenceDepartment of Pathology and Immunology, Washington University School of Medicine, St. Louis, United States.
Connie A MyersDepartment of Pathology and Immunology, Washington University School of Medicine, St. Louis, United States.
Joseph C CorboDepartment of Pathology and Immunology, Washington University School of Medicine, St. Louis, United States.ORCID 0000-0002-9323-7140
Washington University in St. Louis · US

Funding

Research Training Program in the Vision SciencesT32EY013360 · NEI · WASHINGTON UNIVERSITY · PI SHIMING CHEN, Daniel Kerschensteiner · 2000 to 2026
$5.6M
DISSECTING THE CIS-REGULATORY ARCHITECTURE OF THE RETINA BY EPIGENOMIC PROFILINGR01EY025196 · NEI · WASHINGTON UNIVERSITY · PI CORBO, JOSEPH · 2015 to 2019
$2.3M
CONVERTING BIPOLAR CELLS INTO RED-SHIFTED OPTOGENETIC SENSORS FOR RETINAL THERAPYR01EY024958 · NEI · WASHINGTON UNIVERSITY · PI CORBO, JOSEPH, FLANNERY, JOHN GERARD · 2015 to 2019
$2.2M
DECIPHERING THE MECHANISTIC BASIS OF INFRARED VISION FOR OPTOGENETIC APPLICATIONSR01EY026672 · NEI · WASHINGTON UNIVERSITY · PI CORBO, JOSEPH · 2016 to 2019
$1.4M
ELUCIDATING THE CIS-REGULATORY ARCHITECTURE OF RETINAL BIPOLAR CELLSF32EY029571 · NEI · WASHINGTON UNIVERSITY · PI MURPHY, DANIEL P · 2018 to 2019
$123k
NEI NIH HHS F32 EY029571NEI NIH HHS F32EY029571NEI NIH HHS R01 EY024958NEI NIH HHS R01EY024958NEI NIH HHS R01 EY025196NEI NIH HHS R01EY025196NEI NIH HHS R01 EY026672NEI NIH HHS R01EY026672NEI NIH HHS T32 EY013360NEI NIH HHS T32EY013360
6 · The paper itself

Abstract

Multicellular organisms evolved via repeated functional divergence of transcriptionally related sister cell types, but the mechanisms underlying sister cell type divergence are not well understood. Here, we study a canonical pair of sister cell types, retinal photoreceptors and bipolar cells, to identify the key

Indexed as

Evolution, MolecularGene Regulatory NetworksAnimalsBinding SitesChromatinGene Expression ProfilingMicePhotoreceptor CellsRegulatory Sequences, Nucleic AcidRetinal Bipolar CellsChromatinATAC-seqbipolar cellchromosomescis-regulatory elementgene expressiongeneticsgenomicsmousephotoreceptorretinasister cell type

Identifiers

PMID31633482
PMCPMC6802965
OpenAlexW2946122061

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.