Evidence map›Paper›PMID 31633442›Full record

ArticleJournal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research2020

Mechanisms of Innate Immune Activation by a Hybrid Alphavirus-Rhabdovirus Vaccine Platform.

Anthony M Marchese, Carolina Chiale, Safiehkhatoon Moshkani, Michael D Robek

Open access · greenAbstract read
In one paragraph

Article in Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Rational design of self-amplifying virus-like vesicles with Ebola virus glycoprotein as vaccines.Molecular therapy : the journal of the American Society of Gene Therapy · 2024
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Anthony M MarcheseDepartment of Immunology and Microbial Disease, Albany Medical College, Albany, New York.
Carolina ChialeDepartment of Immunology and Microbial Disease, Albany Medical College, Albany, New York.
Safiehkhatoon MoshkaniDepartment of Immunology and Microbial Disease, Albany Medical College, Albany, New York.
Michael D RobekDepartment of Immunology and Microbial Disease, Albany Medical College, Albany, New York.
Albany Medical Center Hospital · US

Funding

Highly Attenuated Vesiculovirus-based Vectors as HBV Therapeutic VaccinesR01AI124006 · NIAID · ALBANY MEDICAL COLLEGE · PI ROBEK, MICHAEL · 2016 to 2020
$2.0M
NIAID NIH HHS R01 AI124006
6 · The paper itself

Abstract

Virus-like vesicles (VLV) are infectious, self-propagating alphavirus-vesiculovirus hybrid vaccine vectors that can be engineered to express foreign antigens to elicit a protective immune response. VLV are highly immunogenic and nonpathogenic

Indexed as

AlphavirusCells, CulturedHumansImmunity, InnateInterferonsRhabdoviridaeViral VaccinesVirus ReplicationInterferonsViral VaccinesSemliki Forest virusvesicular stomatitis virusvesiculovirusviral vaccine vectorvirus-like vesicle

Identifiers

PMID31633442
PMCPMC6987738
OpenAlexW2981718261

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.