Evidence map›Paper›PMID 31633109›Full record

ArticleBrain communications2019

TDP-43 cytoplasmic inclusion formation is disrupted in

Samuel M Lee, Seneshaw Asress, Chadwick M Hales, Marla Gearing, Juan C Vizcarra, Christina N Fournier, David A Gutman, Lih-Shen Chin, Lian Li, Jonathan D Glass

Open access · goldAbstract read
In one paragraph

Article in Brain communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 40 citations in OpenAlex.

  1. Review
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  9. GActa neuropathologica · 2023
    Article
  10. Article
  11. Current advances in neuronal intranuclear inclusion disease.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2023
    Review
  12. Article
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  19. Inducible expression of humanDisease models & mechanisms · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Samuel M LeeDepartment of Neurology, Emory University School of Medicine, Atlanta, GA, USA.
Seneshaw AsressDepartment of Neurology, Emory University School of Medicine, Atlanta, GA, USA.
Chadwick M HalesDepartment of Neurology, Emory University School of Medicine, Atlanta, GA, USA.
Marla GearingDepartment of Neurology, Emory University School of Medicine, Atlanta, GA, USA.
Juan C VizcarraDepartment of Biomedical Engineering, Emory University School of Medicine, Atlanta, GA, USA.
Christina N FournierDepartment of Neurology, Emory University School of Medicine, Atlanta, GA, USA.
David A GutmanDepartment of Biomedical Engineering, Emory University School of Medicine, Atlanta, GA, USA.
Lih-Shen ChinCenter for Neurodegenerative Disease, Emory University School of Medicine, Atlanta, GA, USA.
Lian LiCenter for Neurodegenerative Disease, Emory University School of Medicine, Atlanta, GA, USA.
Jonathan D GlassDepartment of Neurology, Emory University School of Medicine, Atlanta, GA, USA.
Emory University · USGeorgia Institute of Technology · US

Funding

The Emory Alzheimer's Disease CenterP50AG025688 · NIA · EMORY UNIVERSITY · PI LEVEY, ALLAN I · 2005 to 2019
$25.7M
ENNCF - Viral Vector CoreP30NS055077 · NINDS · EMORY UNIVERSITY · PI BASSELL, GARY J · 2008 to 2018
$6.8M
ALZHEIMER'S DISEASE PATHWAYS AND BIOMARKER DISCOVERY BY INTEGRATIVE PROTEOMICS, GLYCOPROTEOMICS, AND GLYCOMICSRF1AG057965 · NIA · EMORY UNIVERSITY · PI LI, LIAN · 2018 to 2018
$3.2M
SIMPLE-regulated trafficking and peripheral neuropathyR01NS092343 · NINDS · EMORY UNIVERSITY · PI LI, LIAN · 2015 to 2019
$1.7M
Investigating RNA splicing factor aggregations in Alzheimer's disease and CTEK08NS087121 · NINDS · EMORY UNIVERSITY · PI HALES, CHADWICK M · 2014 to 2018
$858k
Molecular Analysis of TorsinA Function and DysfunctionR21NS093550 · NINDS · EMORY UNIVERSITY · PI CHIN, LIH-SHEN · 2015 to 2016
$424k
NIA NIH HHS P50 AG025688NIA NIH HHS RF1 AG057965NINDS NIH HHS K08 NS087121NINDS NIH HHS P30 NS055077NINDS NIH HHS R01 NS092343NINDS NIH HHS R21 NS093550
6 · The paper itself

Abstract

The G4C2 hexanucleotide repeat expansion mutation in the

Indexed as

aggresomeamyotrophic lateral sclerosisfrontotemporal dementiainclusion formationTDP-43

Identifiers

PMID31633109
PMCPMC6788139
OpenAlexW2972722099

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.