Evidence map›Paper›PMID 31633087›Full record

ArticleJAMIA open2019

ROMOP: a light-weight R package for interfacing with OMOP-formatted electronic health record data.

Benjamin S Glicksberg, Boris Oskotsky, Nicholas Giangreco, Phyllis M Thangaraj, Vivek Rudrapatna, Debajyoti Datta, Remi Frazier, Nelson Lee, Rick Larsen, Nicholas P Tatonetti and 1 more

Abstract read
In one paragraph

Article in JAMIA open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Clinical Research Informatics.Yearbook of medical informatics · 2020
    Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Benjamin S GlicksbergDepartment of Pediatrics Bakar Computational Health Sciences Institute, University of California San Francisco, San Francisco, California, USA.
Boris OskotskyDepartment of Pediatrics Bakar Computational Health Sciences Institute, University of California San Francisco, San Francisco, California, USA.
Nicholas GiangrecoDepartments of Biomedical Informatics, Systems Biology, and Medicine, Columbia University, New York, New York, USA.
Phyllis M ThangarajDepartments of Biomedical Informatics, Systems Biology, and Medicine, Columbia University, New York, New York, USA.
Vivek RudrapatnaDepartment of Pediatrics Bakar Computational Health Sciences Institute, University of California San Francisco, San Francisco, California, USA.
Debajyoti DattaDepartment of Pediatrics Bakar Computational Health Sciences Institute, University of California San Francisco, San Francisco, California, USA.
Remi FrazierAcademic Research Systems, Department of Enterprise Data Warehouse University of California San Francisco, San Francisco, California, USA.
Nelson LeeAcademic Research Systems, Department of Enterprise Data Warehouse University of California San Francisco, San Francisco, California, USA.
Rick LarsenAcademic Research Systems, Department of Enterprise Data Warehouse University of California San Francisco, San Francisco, California, USA.
Nicholas P TatonettiDepartments of Biomedical Informatics, Systems Biology, and Medicine, Columbia University, New York, New York, USA.
Atul J ButteDepartment of Pediatrics Bakar Computational Health Sciences Institute, University of California San Francisco, San Francisco, California, USA.

Funding

Clinical and Translational Science InstituteUL1TR001872 · NCATS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI COLLARD, HAROLD R, JACOBY, VANESSA · 2016 to 2025
$112.1M
Molecular and Cellular Mechanisms in CancerT32CA108462 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GOGA, ANDREI · 2004 to 2024
$10.4M
Precision Pharmacology and Pharmacovigilance: Leveraging AI to address drug safety knowledge gapsR35GM131905 · NIGMS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Nicholas P Tatonetti · 2019 to 2026
$3.3M
Data-driven subtyping to find patients with drug interactions leading to strokeF30HL140946 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI THANGARAJ, PHYLLIS MARY · 2018 to 2020
$145k
NCATS NIH HHS UL1 TR001872NCI NIH HHS T32 CA108462NHLBI NIH HHS F30 HL140946NIGMS NIH HHS R35 GM131905
6 · The paper itself

Abstract

objectivesElectronic health record (EHR) data are increasingly used for biomedical discoveries. The nature of the data, however, requires expertise in both data science and EHR structure. The Observational Medical Out-comes Partnership (OMOP) common data model (CDM) standardizes the language and structure of EHR data to promote interoperability of EHR data for research. While the OMOP CDM is valuable and more attuned to research purposes, it still requires extensive domain knowledge to utilize effectively, potentially limiting more widespread adoption of EHR data for research and quality improvement. MATERIALS AND

methodsWe have created ROMOP: an R package for direct interfacing with EHR data in the OMOP CDM format.

resultsROMOP streamlines typical EHR-related data processes. Its functions include exploration of data types, extraction and summarization of patient clinical and demographic data, and patient searches using any CDM vocabulary concept.

conclusionROMOP is freely available under the Massachusetts Institute of Technology (MIT) license and can be obtained from GitHub (http://github.com/BenGlicksberg/ROMOP). We detail instructions for setup and use in the Supplementary Materials. Additionally, we provide a public sandbox server containing synthesized clinical data for users to explore OMOP data and ROMOP (http://romop.ucsf.edu).

Identifiers

PMID31633087
PMCPMC6800657

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.