ArticleScience advances2019
Epigenetic initiation of the T
Open access · goldAbstract read
In one paragraph
Article in Science advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 28 citations in OpenAlex.
- The CXXC1-IGFBP6 Axis Maintains Corneal Epithelial Differentiation via H3K4me3-Dependent Transcriptional Activation.Investigative ophthalmology & visual science · 2026Article
- CFP1-mediated H3K4me3 broad domains control early B cell lineage fate determination.Nucleic acids research · 2026Article
- Unveiling the Role of Histone Methyltransferases in Psoriasis Pathogenesis: Insights from Transcriptomic Analysis.International journal of molecular sciences · 2025Article
- Article
- The epigenetic hallmarks of immune cells in cancer.Molecular cancer · 2025Review
- Histone methyltransferases MLL2 and SETD1A/B play distinct roles in H3K4me3 deposition during the transition from totipotency to pluripotency.The EMBO journal · 2025Article
- High placental expression of FLT1, LEP, PHYHIP and IL3RA - In persons of African ancestry with severe preeclampsia.Placenta · 2023Article
- H3K4 trimethylation regulates cancer immunity: a promising therapeutic target in combination with immunotherapy.Journal for immunotherapy of cancer · 2023Review
- Cxxc finger protein 1 maintains homeostasis and function of intestinal group 3 innate lymphoid cells with aging.Nature aging · 2023Article
- CFP1 governs uterine epigenetic landscapes to intervene in progesterone responses for uterine physiology and suppression of endometriosis.Nature communications · 2023Article
- Nsun2 coupling with RoRγt shapes the fate of Th17 cells and promotes colitis.Nature communications · 2023Article
- Enhancing anti-tumor immune responses through combination therapies: epigenetic drugs and immune checkpoint inhibitors.Frontiers in immunology · 2023Review
- Epigenetic modulations of immune cells: from normal development to tumor progression.International journal of biological sciences · 2023Review
- Curcumin regulates the homeostasis of Th17/Treg and improves the composition of gut microbiota in type 2 diabetic mice with colitis.Phytotherapy research : PTR · 2022Article
- Bivalent Regulation and Related Mechanisms of H3K4/27/9me3 in Stem Cells.Stem cell reviews and reports · 2022Review
- Review
- The dynamic broad epigenetic (H3K4me3, H3K27ac) domain as a mark of essential genes.Clinical epigenetics · 2021Review
- Editorial: Genetic and Epigenetic Control of Immune Responses.Frontiers in immunology · 2021Article
- Targeting STAT3 in Cancer Immunotherapy.Molecular cancer · 2020Review
- The Fate of Th17 Cells is Shaped by Epigenetic Modifications and Remodeled by the Tumor Microenvironment.International journal of molecular sciences · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors at 6 institutions in 2 countries.
Feng LinInstitute of Immunology and Bone Marrow Transplantation Center, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.ORCID 0000-0002-1481-3518
Xiaoyu MengInstitute of Immunology and Bone Marrow Transplantation Center, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.ORCID 0000-0002-3190-9490
Yixin GuoInstitute of Immunology and Bone Marrow Transplantation Center, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Wenqiang CaoInstitute of Immunology and Bone Marrow Transplantation Center, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.ORCID 0000-0002-5024-0817
Wanlu LiuZhejiang University-University of Edinburgh Joint Institute, Zhejiang University, Haining, China.
Qiming XiaInstitute of Immunology and Bone Marrow Transplantation Center, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Zhaoyuan HuiInstitute of Immunology and Bone Marrow Transplantation Center, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Jian ChenDepartment of General Surgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Shenghui HongLaboratory Animal Center, Zhejiang University, Hangzhou, China.
Xuliang ZhangLaboratory Animal Center, Zhejiang University, Hangzhou, China.ORCID 0000-0002-8952-8009
Chuan WuExperimental Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0003-2288-353X
Di WangInstitute of Immunology, Zhejiang University School of Medicine, Hangzhou, China.
Jianli WangInstitute of Immunology and Bone Marrow Transplantation Center, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Linrong LuInstitute of Immunology, Zhejiang University School of Medicine, Hangzhou, China.
Wenbin QianInstitute of Hematology, Zhejiang University and Zhejiang Engineering Laboratory for Stem Cell and Immunotherapy, Hangzhou, China.
Lai WeiState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, China.
Lie WangInstitute of Immunology and Bone Marrow Transplantation Center, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.ORCID 0000-0001-5094-012X
First Affiliated Hospital Zhejiang University · CNZhejiang University · CNNational Institutes of Health · USSecond Affiliated Hospital of Zhejiang University · CNSun Yat-sen University · CNZhejiang University-University of Edinburgh Institute · CN
Funding
No grant is acknowledged in the PubMed record.
Abstract
IL-6/STAT3 signaling is known to initiate the T
Indexed as
Cell DifferentiationEpigenesis, GeneticAnimalsCD8-Positive T-LymphocytesCitrobacter rodentiumEncephalomyelitis, Autoimmune, ExperimentalEnterobacteriaceae InfectionsFemaleHistonesInterleukin-6MiceMice, Inbred C57BLMice, KnockoutPromoter Regions, GeneticReceptors, Interleukin-6Signal TransductionCxxc1 protein, mouseHistonesInterleukin-6Receptors, Interleukin-6STAT3 Transcription FactorTrans-Activators
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Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.