Evidence map›Paper›PMID 31632980›Full record

ArticleFrontiers in surgery2019

Clinical Benefits of Combining Different Visualization Modalities in Neurosurgery.

Karl-Michael Schebesch, Katharina Rosengarth, Alexander Brawanski, Martin Proescholdt, Christina Wendl, Julius Höhne, Christian Ott, Hans Lamecker, Christian Doenitz

Abstract read
In one paragraph

Article in Frontiers in surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. A phase I study of a PARP1-targeted topical fluorophore for the detection of oral cancer.European journal of nuclear medicine and molecular imaging · 2021
    Article
  5. Article
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Karl-Michael SchebeschDepartment of Neurosurgery, University Medical Center Regensburg, Regensburg, Germany.
Katharina RosengarthDepartment of Neurosurgery, University Medical Center Regensburg, Regensburg, Germany.
Alexander BrawanskiDepartment of Neurosurgery, University Medical Center Regensburg, Regensburg, Germany.
Martin ProescholdtDepartment of Neurosurgery, University Medical Center Regensburg, Regensburg, Germany.
Christina WendlDepartment of Radiology, University Medical Center Regensburg, Regensburg, Germany.
Julius HöhneDepartment of Neurosurgery, University Medical Center Regensburg, Regensburg, Germany.
Christian OttDepartment of Neurosurgery, University Medical Center Regensburg, Regensburg, Germany.
Hans Lamecker1000shapes GmbH, Berlin, Germany.
Christian DoenitzDepartment of Neurosurgery, University Medical Center Regensburg, Regensburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The prevailing philosophy in oncologic neurosurgery, has shifted from maximally invasive resection to the preservation of neurologic function. The foundation of safe surgery is the multifaceted visualization of the target region and the surrounding eloquent tissue. Recent advancements in pre-operative and intraoperative visualization modalities have changed the face of modern neurosurgery. Metabolic and functional data can be integrated into intraoperative guidance software, and fluorescent dyes under dedicated filters can potentially visualize patterns of blood flow and better define tumor borders or isolated tumor foci. High definition endoscopes enable the depiction of tiny vessels and tumor extension to the ventricles or skull base. Fluorescein sodium-based confocal endomicroscopy, which is under scientific evaluation, may further enhance the neurosurgical armamentarium. We aim to present our institutional workup of combining different neuroimaging modalities for surgical neuro-oncological procedures. This institutional algorithm (IA) was the basis of the recent publication by Haj et al. describing outcome and survival data of consecutive patients with high grade glioma (HGG) before and after the introduction of our Neuro-Oncology Center.

Indexed as

brain tumorsconfocal endomicroscopyCONVIVOfluorescein sodiumfluorescence-guided surgeryKINEVOtumor segmentationYELLOW 560 nm

Identifiers

PMID31632980
PMCPMC6781653

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.