Evidence map›Paper›PMID 31632949›Full record

ArticleFrontiers in chemistry2019

A Novel Heterocyclic System Based on Natural Epoxyalantolactone.

Sergey G Klochkov, Sergey A Pukhov, Svetlana V Afanasieva, Margarita E Neganova, Ivan V Ananiev, Marco Avila-Rodriguez, Vadim V Tarasov, Gjumrakch Aliev

Abstract read
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In one paragraph

Article in Frontiers in chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sergey G KlochkovInstitute of Physiologically Active Compounds of Russian Academy of Sciences, Chernogolovka, Russia.
Sergey A PukhovInstitute of Physiologically Active Compounds of Russian Academy of Sciences, Chernogolovka, Russia.
Svetlana V AfanasievaInstitute of Physiologically Active Compounds of Russian Academy of Sciences, Chernogolovka, Russia.
Margarita E NeganovaInstitute of Physiologically Active Compounds of Russian Academy of Sciences, Chernogolovka, Russia.
Ivan V AnanievInstitute of Organoelement Compounds of Russian Academy of Sciences, Moscow, Russia.
Marco Avila-RodriguezClinic Sciences Department, Health Sciences Faculty, University of Tolima, Ibagué, Colombia.
Vadim V TarasovDepartment of Pharmacology and Pharmacy, Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia.
Gjumrakch AlievInstitute of Physiologically Active Compounds of Russian Academy of Sciences, Chernogolovka, Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Natural sesquiterpene lactones which contain an exocyclic methylene group in the β-position of the lactone ring react readily with N-nucleophiles. When studying the reaction of the natural epoxyalantolactone with the primary amines we demonstrate the formation of a new heterocyclic system-the hydrogenated benzo[g]furo[4,3,2-cd]indol-3(1H)-one. Spectral data on the characteristics of the synthesized compounds are presented. The data on the reaction mechanisms and its applicability for the preparation are discussed.

Indexed as

epoxyalantolactoneMichael reactionnew heterocyclic systemsesquiterpene lactonessynthesis

Identifiers

PMID31632949
PMCPMC6779722

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