Evidence map›Paper›PMID 31632546›Full record

ArticleAmerican journal of translational research2019

Effects of microbubble-enhanced ultrasound combined with prothrombin on microwave ablation in rabbit VX2 liver tumor.

Ying Shi, Ping Yan, Zhenli Luo, Junwang Zhang, Qiling Liu, Xiaodong Zhou

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in American journal of translational research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 80% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Ying ShiDepartment of Ultrasound, The Second Hospital of Shanxi Medical University Taiyuan 030001, Shanxi, China.
Ping YanDepartment of Biochemistry and Molecular Biology, Shanxi Medical University Taiyuan 030001, Shanxi, China.
Zhenli LuoDepartment of Cardiology, The First Hospital of Yuncheng Yuncheng 044000, China.
Junwang ZhangDepartment of Gastroenterology, The Second Hospital of Shanxi Medical University Taiyuan 030001, Shanxi, China.
Qiling LiuDepartment of Epidemic and Health Statistics, College of Public Health in Shaanxi University of Chinese Medicine Xi'an 712046, Shaanxi, China.
Xiaodong ZhouDepartment of Ultrasound, Xijing Hospital, The Fourth Military Medical University Xi'an 710032, Shaanxi, China.
Shanxi Medical University · CNShaanxi University of Chinese Medicine · CNXijing Hospital · CNYuncheng University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aimed to investigate effects of microbubble-enhanced ultrasound (MEUS) combined with prothrombin on microwave ablation (MWA) on VX2 liver tumors in a rabbit model.

methods80 rabbits with VX2 liver tumors were randomly divided into Group A (sham + NS), Group B (sham + NS + P), Group C (MEUS), and Group D (PMEUS). After treatment, targeted liver tumors were ablated with MWA. On 0, 3, 7 and 14 d, volume of coagulated area was measured. Tissues in ablated area, transition area and surrounding area were collected.

resultsOn 0, 3, 7 and 14 d, coagulated volume in Group D was larger than remaining three groups (

conclusionsMEUS combined with prothrombin on MWA can significantly expand ablation volume, enhance the necrosis of ablated tissues, inhibit tumor growth/metastasis and improve therapeutic effect of MWA on rabbit VX2 liver tumors.

Indexed as

Microbubblemicrowave ablationprothrombinrabbitVX2 liver tumor

Identifiers

PMID31632546
PMCPMC6789283
OpenAlexW2988120351

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.