ArticleAmerican journal of translational research2019
Surface modification of decellularized trachea matrix with collagen and laser micropore technique to promote cartilage regeneration.
Article in American journal of translational research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed.
- Current status, trend and progress of stem cells in tracheal tissue engineering research: an overview and perspectives.Stem cell research & therapy · 2025Review
- Cartilage Laser Engraving for Fast-Track Tissue Engineering of Auricular Grafts.International journal of molecular sciences · 2024Article
- An Injectable Platform of Engineered Cartilage Gel and Gelatin Methacrylate to Promote Cartilage Regeneration.Frontiers in bioengineering and biotechnology · 2022Article
- Enhancing Stem Cell-Based Therapeutic Potential by Combining Various Bioengineering Technologies.Frontiers in cell and developmental biology · 2022Review
- 3D Printed Biomimetic PCL Scaffold as Framework Interspersed With Collagen for Long Segment Tracheal Replacement.Frontiers in cell and developmental biology · 2021Article
- A Biomimetic Biphasic Scaffold Consisting of Decellularized Cartilage and Decalcified Bone Matrixes for Osteochondral Defect Repair.Frontiers in cell and developmental biology · 2021Article
- Electrospun nanofibrous membrane of fish collagen/polycaprolactone for cartilage regeneration.American journal of translational research · 2020Article
- Article
- Tissue-engineered composite tracheal grafts create mechanically stable and biocompatible airway replacements.Journal of tissue engineeringArticle
- Regeneration of partially decellularized tracheal scaffolds in a mouse model of orthotopic tracheal replacement.Journal of tissue engineeringArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The repair of long-segment tracheal defects remains a significant clinical challenge, to which, optimal biologically functioning tracheal alternatives may serve as a solution. Tissue-engineered trachea, regenerated from a decellularized trachea matrix using the laser micropore technique (LDTM), demonstrates the possibility of developing optimal tracheal substitutes, which retain the original tubular shape and adequate cartilage regeneration ability of trachea. However, the strict requirement with respect to the implantation cell density restricts the clinical translation of the LDTM, which has a low cell adherence rate. To overcome this problem, we propose a novel strategy involving collagen to modify the LDTM surface in order to enhance cell retention efficiency and promote homogeneous tracheal cartilage regeneration. The current results show that the modified LDTM significantly improves cell-seeding efficiency; moreover, it achieved stable cell retention and homogenous cell distribution. Additionally, at a relatively low implantation cell density (5.0 × 10
Indexed as
Identifiers
31632518PMC6789231What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.