Evidence map›Paper›PMID 31632342›Full record

ArticleFrontiers in neurology2019

The Association Between Distinct Frontal Brain Volumes and Behavioral Symptoms in Mild Cognitive Impairment, Alzheimer's Disease, and Frontotemporal Dementia.

Antti Cajanus, Eino Solje, Juha Koikkalainen, Jyrki Lötjönen, Noora-Maria Suhonen, Ilona Hallikainen, Ritva Vanninen, Päivi Hartikainen, Matteo de Marco, Annalena Venneri and 3 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neurology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 57 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Antti CajanusInstitute of Clinical Medicine, Neurology, University of Eastern Finland, Kuopio, Finland.
Eino SoljeInstitute of Clinical Medicine, Neurology, University of Eastern Finland, Kuopio, Finland.
Juha KoikkalainenCombinostics Ltd., Tampere, Finland.
Jyrki LötjönenCombinostics Ltd., Tampere, Finland.
Noora-Maria SuhonenMRC Oulu, Oulu University Hospital, Oulu, Finland.
Ilona HallikainenInstitute of Clinical Medicine, Neurology, University of Eastern Finland, Kuopio, Finland.
Ritva VanninenDepartment of Radiology, Kuopio University Hospital, Kuopio, Finland.
Päivi HartikainenNeurocenter, Neurology, Kuopio University Hospital, Kuopio, Finland.
Matteo de MarcoDepartment of Neuroscience, University of Sheffield, Sheffield, United Kingdom.
Annalena VenneriDepartment of Neuroscience, University of Sheffield, Sheffield, United Kingdom.
Hilkka SoininenInstitute of Clinical Medicine, Neurology, University of Eastern Finland, Kuopio, Finland.
Anne M RemesMRC Oulu, Oulu University Hospital, Oulu, Finland.
Anette HallInstitute of Clinical Medicine, Neurology, University of Eastern Finland, Kuopio, Finland.
University of Eastern Finland · FIKuopio University Hospital · FIOulu University Hospital · FIUniversity of Sheffield · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Our aim was to investigate the association between behavioral symptoms of agitation, disinhibition, irritability, elation, and aberrant motor behavior to frontal brain volumes in a cohort with various neurodegenerative diseases. A total of 121 patients with mild cognitive impairment (MCI,

Indexed as

Alzheimer's diseasebehavioral symptomsfrontotemporal dementiamagnetic resonance imagingmild cognitive impairment

Identifiers

PMID31632342
PMCPMC6786130
OpenAlexW2978702276

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.