ReviewSeminars in plastic surgery2019
Evidence for the Use of Acellular Dermal Matrix in Implant-Based Breast Reconstruction.
Review in Seminars in plastic surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.
- Statistical fragility of outcomes in acellular dermal matrix literature: A systematic review of randomized controlled trials.Journal of plastic, reconstructive & aesthetic surgery : JPRAS · 2024Pooled it
- A randomized, controlled, double-blinded trial on the effects of acellular dermal matrices on the functional assessment and qualitative satisfaction of split-thickness skin grafts.Scientific reports · 2025Trial
- Clinical Performance of GalaFLEX® (Poly-4-Hydroxybutyrate) Scaffold Application in Aesthetic and Reconstructive Breast Surgery: A Retrospective Study.Aesthetic plastic surgery · 2026Article
- Clinical safety and breast symmetry after injectable acellular dermal fibers reconstruction: an MR-based volumetric study.Gland surgery · 2026Article
- Prospective Observational Study of Supercritical Carbon Dioxide-Processed Acellular Dermal Matrix in Implant-Based Breast Reconstruction.Archives of plastic surgery · 2026Article
- Pre-Pectoral Tissue Expander and Acellular Dermal Matrix for a Two-Stage Muscle Sparing Breast Reconstruction: Indications, Surgical Technique and Clinical Outcomes with Histological and Ultrasound Follow-Up-A Population-Based Cohort Study.Aesthetic plastic surgery · 2025Article
- Article
- Use of Fascia Lata as Matrix for Subpectoral Breast Reconstruction.Plastic and reconstructive surgery. Global open · 2024Article
- Volume replacement in tumor plastic surgery and breast-conserving surgery using 3D grid and strip‑shaped acellular dermal matrix: Two case reports.Experimental and therapeutic medicine · 2024Article
- Chyle Leak Management in the Setting of Tissue Expander Breast Reconstruction with Acellular Dermal Matrix: Case Series and Literature Review.Plastic and reconstructive surgery. Global open · 2024Article
- Development and validation of cryopreserved or freeze-dried decellularized human dermis for transplantation.Cell and tissue banking · 2024Article
- Reinforcement of a Subcutaneous Pocket for Implantable Cardioverter Defibrillator Insertion Using Acellular Dermal Matrix: A Case Report.Journal of clinical medicine · 2024Article
- Early Complications in Prepectoral Breast Reconstructions with and without Acellular Dermal Matrix: A Preliminary Analysis of Outcomes.Plastic and reconstructive surgery · 2024Article
- The Future of Microsurgery: Vascularized Composite Allotransplantation and Engineering Vascularized Tissue.Journal of hand and microsurgery · 2024Article
- Decellularization and Their Significance for Tissue Regeneration in the Era of 3D Bioprinting.ACS omega · 2024Review
- Assessment of inflammatory suppression and fibroblast infiltration in tissue remodelling by supercritical COFrontiers in bioengineering and biotechnology · 2024Article
- Comparison of the Characteristics of Three Acellular Dermal Matrices Subjected to Distinct Processing Methods Using Five Types of Histochemical Staining.Aesthetic plastic surgery · 2023Article
- Optimizing Acellular Dermal Matrix Integration in Heterologous Breast Reconstructive Surgery: Surgical Tips and Post-Operative Management.Medicina (Kaunas, Lithuania) · 2023Article
- Implant-Based Breast Reconstruction after Risk-Reducing Mastectomy in BRCA Mutation Carriers: A Single-Center Retrospective Study.Healthcare (Basel, Switzerland) · 2023Article
- Should Acellular Dermal Matrices Be Used for Implant-based Breast Reconstruction after Mastectomy? Clinical Recommendation Based on the GRADE Approach.Plastic and reconstructive surgery. Global open · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acellular dermal matrices (ADMs) are tissue grafts that have been specially processed to remove all cellular components. These machined biological scaffolds have become popular in a variety of surgical settings due to their rapid incorporation into living tissue. As ADMs are highly malleable and cause minimal inflammation, they have come to serve as a useful tool in implant-based breast reconstruction procedures. The major benefits of using an ADM in this setting include superior initial breast contouring, decreased risk of capsular contracture after implant insertion, and consistent sustained positioning of the reconstructed breast. Despite these advantages, these tissue grafts are foreign to the host, and postoperative complications following ADM insertion, including infection and seroma, have been well documented. When considering using ADMs in this setting, it is important to first consider patient-specific factors that could preclude their use, such as low body mass index, small breasts, or a history of radiation exposure to the breast tissue. ADM grafts are also expensive, which may present another barrier to their use. Review of the literature ultimately suggests a continued role for ADMs in implant-based breast reconstruction, and continued research in this field is warranted.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.