Evidence map›Paper›PMID 31632126›Full record

ArticleThe application of clinical genetics2019

Genetic Analysis Of

Rami Alkhatib, Nada Abudhaim, Laith Al-Eitan, Nour Abdo, Asem Alqudah, Hatem Aman

Abstract read
In one paragraph

Article in The application of clinical genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Polymorphic variants ofInternational journal of ophthalmology · 2025
    Article
  2. Article
  3. Article
  4. Association ofMolecular vision · 2022
    Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rami AlkhatibDepartment of Biotechnology and Genetic Engineering, Jordan University of Science and Technology, Irbid 22110, Jordan.ORCID 0000-0003-1635-8624
Nada AbudhaimDepartment of Biotechnology and Genetic Engineering, Jordan University of Science and Technology, Irbid 22110, Jordan.
Laith Al-EitanDepartment of Applied Biological Sciences, Jordan University of Science and Technology, Irbid 22110, Jordan.ORCID 0000-0003-0064-0190
Nour AbdoDepartment of Public Health, Faculty of Medicine, Jordan University of Science and Technology, Irbid 22110, Jordan.
Asem AlqudahDepartment of Ophthalmology, Faculty of Medicine, Jordan University of Science and Technology, Irbid 22110, Jordan.
Hatem AmanDepartment of Biotechnology and Genetic Engineering, Jordan University of Science and Technology, Irbid 22110, Jordan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGlaucoma is a neurodegenerative disease that leads to progressive loss of retinal ganglion cells, causing irreversible visual field defects. At the present time, glaucoma is clinically defined but the exact etiology is unknown. The aim of this study is to genotype rs2472493 and rs2487032 SNIPs within

methodsDNA was extracted from both patients and controls according to a well-established procedure. Then, DNA was amplified by PCR using specific primers for this gene. Analysis of polymorphisms was carried out by using DNA sequencing genotyping method.

resultsThe results showed that the two SNPs (rs2472493 and rs2487032) located upstream of

conclusionThis study is the first of its kind to reveal no genetic association between

Indexed as

ABCA1glaucomaJordanian Arabpolymorphismsprimers

Identifiers

PMID31632126
PMCPMC6783111

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.