Evidence map›Paper›PMID 31632117›Full record

ArticleDiabetes, metabolic syndrome and obesity : targets and therapy2019

A Novel Indicator Of Lipid Accumulation Product Associated With Metabolic Syndrome In Chinese Children And Adolescents.

Yifei Zhang, Jingyao Hu, Zhiqiang Li, Ting Li, Manman Chen, Lu Wu, Wenmin Liu, Hui Han, Rongying Yao, Lianguo Fu

Open access · goldAbstract read
In one paragraph

Article in Diabetes, metabolic syndrome and obesity : targets and therapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
7.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Yifei ZhangDepartment of Child and Adolescent Health, School of Public Health, Bengbu Medical College, Bengbu, People's Republic of China.
Jingyao HuDepartment of Child and Adolescent Health, School of Public Health, Bengbu Medical College, Bengbu, People's Republic of China.
Zhiqiang LiDepartment of Child and Adolescent Health, School of Public Health, Bengbu Medical College, Bengbu, People's Republic of China.
Ting LiDepartment of Child and Adolescent Health, School of Public Health, Bengbu Medical College, Bengbu, People's Republic of China.
Manman ChenDepartment of Child and Adolescent Health, School of Public Health, Bengbu Medical College, Bengbu, People's Republic of China.
Lu WuDepartment of Child and Adolescent Health, School of Public Health, Bengbu Medical College, Bengbu, People's Republic of China.
Wenmin LiuDepartment of Child and Adolescent Health, School of Public Health, Bengbu Medical College, Bengbu, People's Republic of China.
Hui HanDepartment of Child and Adolescent Health, School of Public Health, Bengbu Medical College, Bengbu, People's Republic of China.
Rongying YaoDepartment of Child and Adolescent Health, School of Public Health, Bengbu Medical College, Bengbu, People's Republic of China.
Lianguo FuDepartment of Child and Adolescent Health, School of Public Health, Bengbu Medical College, Bengbu, People's Republic of China.
Bengbu Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe lipid accumulation product (LAP) is a powerful marker for predicting metabolic syndrome (MS) in adults. The present study aimed to propose a novel indicator, the children's lipid accumulation product (CLAP), and to assess its association with MS among Chinese children and adolescents.

methodsA total of 683 Chinese children aged 8-15 years were recruited using a stratified cluster sampling method in this cross-sectional study. The presence of MS was defined according to the NCEP-ATP III criteria. The effects of BMI, WHtR and the CLAP for predicting MS were compared using logistic regression models and receiver operating characteristic (ROC) curves.

resultsThe prevalence of MS was 5.1% (6.6% and 3.5% among boys and girls, respectively). Overall obesity (based on BMI), abdominal obesity (based on WHtR) and CLAP≥P75 were significantly associated with an increased risk of MS (ORs (95% CIs) were 143.79 (18.78-1101.22), 86.83 (27.19-277.27), 150.75 (20.11-1130.19), respectively). The area under the ROC curve (AUC) for the CLAP was higher than that for BMI and WHtR for predicting MS, with AUC (95% CI) values of 0.944 (0.913-0.975), 0.895 (0.864-0.927), and 0.928 (0.903-0.953), respectively.

conclusionThe children's lipid accumulation product (CLAP) was an effective indicator associated with MS in Chinese children and adolescents and was better than BMI and WHtR for predicting MS.

Indexed as

childhood obesitylipid metabolismmetabolic syndrome

Identifiers

PMID31632117
PMCPMC6791402
OpenAlexW2980140057

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.