ArticleInternational journal of nanomedicine2019
Conjugation Of EGCG And Chitosan NPs As A Novel Nano-Drug Delivery System.
Article in International journal of nanomedicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Aptamer-functionalized EGCG nanocarrier for neutrophil-targeted AKBA delivery promotes anxiety-related fracture healing.Bioactive materials · 2027Article
- Synergistic Effects Between Chitooligosaccharide-Epigallocatechin Gallate Conjugate and Nisin on Inhibition of Seafood-AssociatedFoods (Basel, Switzerland) · 2026Article
- Article
- Optimized Epigallocatechin Gallate Delivery and Adipogenesis Inhibition through Fluorescent Mesoporous Nanocarriers.Biomaterials research · 2024Article
- Chitosan-Based Nanogels Designed for Betanin-Rich Beetroot Extract Transport: Physicochemical and Biological Aspects.Polymers · 2023Article
- Chitosan Nanoparticle/Simvastatin for Experimental Maxillary Bony Defect Healing: A Histological and Histomorphometrical Study.Biomimetics (Basel, Switzerland) · 2023Article
- Polymeric Nanoparticles for Delivery of Natural Bioactive Agents: Recent Advances and Challenges.Polymers · 2023Review
- Epigallocatechin-3-gallate chitosan nanoparticles in an extender improve the antioxidant capacity and post-thawed quality of Kacang goat semen.F1000Research · 2023Article
- Synthesis of bee venom loaded chitosan nanoparticles for anti-MERS-COV and multi-drug resistance bacteria.International journal of biological macromolecules · 2023Article
- Immunogenicity of inactivatedIranian journal of basic medical sciences · 2022Article
- Metagenomics Approach to the Intestinal Microbiome Structure and Abundance in High-Fat-Diet-Induced Hyperlipidemic Rat Fed with (-)-Epigallocatechin-3-Gallate Nanoparticles.Molecules (Basel, Switzerland) · 2022Article
- Green Synthesis of Silymarin-Chitosan Nanoparticles as a New Nano Formulation with Enhanced Anti-Fibrotic Effects against Liver Fibrosis.International journal of molecular sciences · 2022Article
- Nanocarriers Based on Gold Nanoparticles for Epigallocatechin Gallate Delivery in Cancer Cells.Pharmaceutics · 2022Article
- An Up-to-Date Review of Natural Nanoparticles for Cancer Management.Pharmaceutics · 2021Review
- Article
- Chitosan Nanoparticles for Antiviral Drug Delivery: A Novel Route for COVID-19 Treatment.International journal of nanomedicine · 2021Review
- Biocompatibility analysis of high molecular weight chitosan obtained fromBiochemistry and biophysics reports · 2020Article
- Catechins within the Biopolymer Matrix-Design Concepts and Bioactivity Prospects.Antioxidants (Basel, Switzerland) · 2020Review
- Preparation of Puerarin Chitosan Oral Nanoparticles by Ionic Gelation Method and Its Related Kinetics.Pharmaceutics · 2020Article
- Enhanced Chemotherapeutic Efficacy of PLGA-Encapsulated Epigallocatechin Gallate (EGCG) Against Human Lung Cancer.International journal of nanomedicine · 2020Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeChitosan nanoparticles (CS NPs) have been used as a good vehicle for nano-drug delivery due to their good physicochemical properties. Epigallocatechin-3-gallate (EGCG), one of the major active ingredients of green tea, is a natural antioxidant that helps in reducing and preventing cell damage and fighting cancer, plus providing other benefits. The aim of this study is to optimise the preparation parameters in terms of the physical characteristics and stability in CS/EGCG NPs conjugation.
resultsThe conjugation of CS/EGCGNPs was obtained by means of Poloxamer 188. The average CS/EGCG NPs complex was of size 117.8±38.71nm with a surface charge of +67.8±4.38mV and isoelectric point at pH 7.61.
conclusionIn conclusion, NPs produced were stable at 4°C with nanometric size, good polydispersity, good loading and efficiency, envisaging to be a possible candidate for nano-therapeutic delivery system against hepatic fibrosis.
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