ArticleInternational journal of nanomedicine2019
Glucose oxidase complexed gold-graphene nanocomposite on a dielectric surface for glucose detection: a strategy for gestational diabetes mellitus.
Article in International journal of nanomedicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- A cross-sectional clinical analysis on diabetic foot ulcer and associated risk management.Indian journal of pharmacology · 2026Article
- Carbon Material Hybrid Construction on an Aptasensor for Monitoring Surgical Tumors.Journal of analytical methods in chemistry · 2022Article
- Emerging Theranostic Nanomaterials in Diabetes and Its Complications.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022Review
- Theranostic Advances of Bionanomaterials against Gestational Diabetes Mellitus: A Preliminary Review.Journal of functional biomaterials · 2021Review
- Molecular prospect of type-2 diabetes: Nanotechnology based diagnostics and therapeutic intervention.Reviews in endocrine & metabolic disorders · 2021Review
- Enzyme Immobilization on Gold Nanoparticles for Electrochemical Glucose Biosensors.Nanomaterials (Basel, Switzerland) · 2021Review
- Longitudinal Zeolite-Iron Oxide Nanocomposite Deposited Capacitance Biosensor for Interleukin-3 in Sepsis Detection.Nanoscale research letters · 2021Article
- Graphene Oxide-Gold Star Construct on Triangular Electrodes for Alzheimer's Disease Identification.Journal of analytical methods in chemistry · 2021Article
- Targeted DNA complementation on a 1,1'-carbonyldiimidazole-functionalized surface for identifying3 Biotech · 2020Article
- Fly Ash-Based Zeolite-Complexed Polyethylene-Glycol on an Interdigitated Electrode Surface for High-Performance Determination of Diabetes Mellitus.International journal of nanomedicine · 2020Article
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7 authors.
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Abstract
backgroundGestational diabetes mellitus is a commonly occurring metabolic disorder during pregnancy, affecting >4% of pregnant women. It is generally defined as the intolerance of glucose with the onset or initial diagnosis during pregnancy. This illness affects the placenta and poses a threat to the baby as it affects the supply of proper oxygen and nutrients. PURPOSE: Due to the high percentage of affected pregnant women, it should be mandatory to evaluate glucose levels during pregnancy and there is a need for a continuous monitoring system.
methodsHerein, the investigators modified the interdigitated (di)electrodes (IDE) sensing surface to detect the glucose on covalently immobilized glucose oxidase (GOx) with the graphene. The characterization of graphene and gold nanoparticle (GNP) was performed by high-resolution microscopy.
resultsSensitivity was found to be 0.06 mg/mL and to enhance the detection, GOx was complexed with GNP. GNP-GOx was improved the sensitive detection twofold from 0.06 to 0.03 mg/mL, and it also displayed higher levels of current changes at all the concentrations of glucose that were tested. High-performance of the above IDE sensing system was attested by the specificity, reproducibility and higher sensitivity detections. Further, the linear regression analysis indicated the limit of detection to be between 0.02 and 0.03 mg/mL.
conclusionThis study demonstrated the potential strategy with nanocomposite for diagnosing gestational diabetes mellitus.
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