Evidence map›Paper›PMID 31631990›Full record

ArticleClinical interventions in aging2019

12-Month Teriparatide Treatment Reduces New Vertebral Compression Fractures Incidence And Back Pain And Improves Quality Of Life After Percutaneous Kyphoplasty In Osteoporotic Women.

Meng Kong, Chuanli Zhou, Kai Zhu, Yiran Zhang, Mengxiong Song, Hao Zhang, Qihao Tu, Xuexiao Ma

Open access · goldAbstract read
In one paragraph

Article in Clinical interventions in aging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 26 citations in OpenAlex.

  1. Impact of anti-osteoporosis medication on refracture prevention following osteoporotic vertebral fracture: a systematic review and meta-analysis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025
    Pooled it
  2. Risk factors for new vertebral fracture after percutaneous vertebroplasty or kyphoplasty for osteoporotic vertebral compression fractures (OVCFs): an updated systematic review and meta-analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025
    Pooled it
  3. Bracing versus balloon kyphoplasty for acute osteoporotic vertebral fractures with poor prognostic radiological factors: a propensity score-matched comparison.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
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  15. Timing of symptomatic subsequent vertebral compression fracture associated with different demographic factors.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2022
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  18. Abaloparatide and the Spine: A Narrative Review.Clinical interventions in aging · 2020
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Meng KongDepartment of Spinal Surgery, Affiliated Hospital of Qingdao University, Qing'dao, Shandong Province 266000, China.ORCID 0000-0002-1466-9667
Chuanli ZhouDepartment of Spinal Surgery, Affiliated Hospital of Qingdao University, Qing'dao, Shandong Province 266000, China.
Kai ZhuDepartment of Spinal Surgery, Affiliated Hospital of Qingdao University, Qing'dao, Shandong Province 266000, China.
Yiran ZhangDepartment of Spinal Surgery, Affiliated Hospital of Qingdao University, Qing'dao, Shandong Province 266000, China.
Mengxiong SongDepartment of Spinal Surgery, Affiliated Hospital of Qingdao University, Qing'dao, Shandong Province 266000, China.
Hao ZhangDepartment of Spinal Surgery, Affiliated Hospital of Qingdao University, Qing'dao, Shandong Province 266000, China.
Qihao TuDepartment of Spinal Surgery, Affiliated Hospital of Qingdao University, Qing'dao, Shandong Province 266000, China.
Xuexiao MaDepartment of Spinal Surgery, Affiliated Hospital of Qingdao University, Qing'dao, Shandong Province 266000, China.
Qingdao University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeDefine the effectiveness of teriparatide (TPTD) treatment on reducing the incidence of new vertebral compression fractures (NVCFs) and back pain and improving quality of life after percutaneous kyphoplasty (PKP).

methodsTwo years of clinical follow-up data from primary osteoporotic women who had experienced initial osteoporotic vertebral compression fractures (OVCFs) and received PKP plus 12-month TPTD (n=113) or basic treatment (BT) of calcium and vitamin D supplements (n=208) were retrospectively collected. The risk of NVCFs over each 6-month period in the TPTD group was evaluated and compared with the BT group using a logistic regression. Health-related quality of life (HRQoL, EQ-5D questionnaire), back pain [100 mm visual analog scale (VAS)] and bone mineral density (BMD) of the spine were analyzed using linear mixed models for repeated measures (LMMRM).

resultsLogistic regression analysis adjusting for baseline characteristics showed that patients in the TPTD group had a lower risk of NVCFs compared with those receiving BT during the final three observation intervals (6-12 months, OR=0.189, 95% CI=0.030-0.681,

conclusionIn routine clinical practice, for patients with OVCFs who receive the PKP procedure, TPTD treatment may be a preferable subsequent therapy because of its ability to reduce the incidence of NVCFs and sustain a high quality of life and back pain alleviation.

Indexed as

Quality of LifeAgedAged, 80 and overBone Density Conservation AgentsFemaleFractures, CompressionHumansKyphoplastyMiddle AgedOsteoporosis, PostmenopausalOsteoporotic FracturesRetrospective StudiesTeriparatideTreatment OutcomeBone Density Conservation AgentsTeriparatideback painosteoporosis vertebral fracturesPKPquality of lifeteriparatide

Identifiers

PMID31631990
PMCPMC6778479
OpenAlexW2975380263

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.