ArticleDrug design, development and therapy2019
Evaluation of the effect of long-term use of antidepressants in the SSRI group on bone density with dental volumetric tomography.
Article in Drug design, development and therapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 11 citations in OpenAlex.
- The selective serotonin reuptake inhibitor escitalopram oxalate negatively impacts the fracture healing in healthy adults and in osteoporotic rats.Scientific reports · 2025Article
- The evaluation of the effect of long-term antihypertensive drug usage on bone density with dental volumetric tomography.Journal of clinical and experimental dentistry · 2024Article
- Histological, immunohistochemical and radiographic evaluation of Amitriptyline administration on the periodontium of albino rats (An experimental study).The Saudi dental journal · 2022Article
- Regulation of Antidepressant Prescription for the Effective Treatment of Mental Disorders in Turkey: A Narrative Review.Psychiatry and clinical psychopharmacology · 2022Review
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimThe present study aims to employ dental volumetric tomography to examine bone mineral density among men that used antidepressants in the SSRI group for a long time.
methodThe present study was conducted through the utilisation of data related to patients that presented to the Faculty of Dentistry of Dicle University and had a dental volumetric tomography (DVT) scan for any reason. The patients were divided into 2 groups based on the use of antidepressants: Group 1 included 68 patients as the control group, and Group 2 consisted of 68 patients that used antidepressants. Radiomorphometric measurements were performed on DVT data: DVT-Mandibular Index (DVT-MI), DVT-Cortical Index (DVT-CI), Hounsfıeld Unit (HU) CORTICAL, and HU SPONGIOSIS values were calculated.
resultsThe group of patients that used antidepressants exhibited a significant increase in DVT CI and a significant decrease in HU CORTICAL, HU SPONGIOSIS and DVT MI values. These findings were suggestive of osteoporosis.
conclusionLong-term use of antidepressants should be taken into consideration as a risk factor for osteoporosis in men.
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