Evidence map›Paper›PMID 31631967›Full record

ArticleClinical ophthalmology (Auckland, N.Z.)2019

Objective assessment of optical quality in dry eye disease using a double-pass imaging system.

Larissa Gouvea, George Oral Waring, Ashley Brundrett, Michelle Crouse, Karolinne Maia Rocha

Open access · goldAbstract read
In one paragraph

Article in Clinical ophthalmology (Auckland, N.Z.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Trial
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  3. Dynamic Tear Film Stability Assessed via an Open-View Double-Pass Imaging System.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Larissa GouveaStorm Eye Institute, Medical University of South Carolina, Charleston, SC, USA.
George Oral WaringWaring Vision Institute, Mount Pleasant, SC, USA.
Ashley BrundrettStorm Eye Institute, Medical University of South Carolina, Charleston, SC, USA.
Michelle CrouseDepartment of Internal Medicine, Tulane University School of Medicine, New Orleans, LA, USA.
Karolinne Maia RochaStorm Eye Institute, Medical University of South Carolina, Charleston, SC, USA.
Medical University of South Carolina · USTulane University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo assess optical quality dynamics using a double-pass (DP) system in patients with dry eye disease (DED).

methodsSeventy-six eyes with DED and 44 control subjects were enrolled in this study. Each patient underwent ocular surface evaluation including fluorescein corneal staining and Schirmer's II test. Ocular Surface Disease Index (OSDI) questionnaire was used to assess subjective symptoms. Optical quality dynamics and tear film instability was analyzed using a DP system (HD Analyzer

resultsThe DED group had pronounced impairment of optical quality compared to the control group. Mean OSI (4.29±4.07), minimum (3.22±3.51) and maximum (5.72±4.52) OSI, ΔOSI (2.50±1.96), OSDI score (36.94±16.55), and fluorescein corneal staining (0.79±0.96) were statistically significantly higher than controls (

conclusionDP imaging system provides an objective measurement of the visual quality in DED. Tear film instability may be assessed by dynamic changes of OSI over 20 s. In particular, the highest OSI values were observed in the ladder pattern group.

Indexed as

double-pass imaging systemdry eye diseasefluorescein corneal stainingobjective scatter indexocular surface disease indexquality of visionSchirmer’s testtear film analysis

Identifiers

PMID31631967
PMCPMC6790329
OpenAlexW2979391666

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.