Evidence map›Paper›PMID 31631729›Full record

ArticleJournal of the American Heart Association2019

Incremental Value of Computed Tomography Perfusion for Final Infarct Prediction in Acute Ischemic Cerebellar Stroke.

Matthias P Fabritius, Paul Reidler, Matthias F Froelich, Lukas T Rotkopf, Thomas Liebig, Lars Kellert, Katharina Feil, Steffen Tiedt, Philipp M Kazmierczak, Kolja M Thierfelder and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Matthias P FabritiusDepartment ot Radiology University Hospital, LMU Munich Munich Germany.
Paul ReidlerDepartment ot Radiology University Hospital, LMU Munich Munich Germany.
Matthias F FroelichDepartment ot Radiology University Hospital, LMU Munich Munich Germany.
Lukas T RotkopfDepartment ot Radiology University Hospital, LMU Munich Munich Germany.
Thomas LiebigDepartment of Neuroradiology University Hospital LMU Munich Germany.
Lars KellertDepartment of Neurology University Hospital LMU Munich Germany.
Katharina FeilDepartment of Neurology University Hospital LMU Munich Germany.
Steffen TiedtInstitute for Stroke and Dementia Research University Hospital LMU Munich Germany.
Philipp M KazmierczakDepartment ot Radiology University Hospital, LMU Munich Munich Germany.
Kolja M ThierfelderInstitute of Diagnostic and Interventional Radiology Pediatric Radiology and Neuroradiology University Medical Center Rostock Germany.
Daniel Puhr-WesterheideDepartment ot Radiology University Hospital, LMU Munich Munich Germany.
Wolfgang G KunzDepartment ot Radiology University Hospital, LMU Munich Munich Germany.
LMU Klinikum · DELudwig-Maximilians-Universität München · DEHeidelberg University · DERotkreuzklinikum München · DEUniversity of Rostock · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background The diagnosis of ischemic cerebellar stroke is challenging because of nonspecific symptoms and very limited accuracy of commonly applied computed tomography (CT) imaging. Advances in CT perfusion imaging provide increasing value in the detection of posterior circulation stroke, but the prognostic value remains unclear. We aimed to identify imaging parameters that predict morphologic outcome in cerebellar stroke patients using advanced CT including whole-brain CT perfusion (WB-CTP). Methods and Results We selected all subjects with cerebellar WB-CTP perfusion deficits and follow-up-confirmed cerebellar infarction from a consecutive cohort with suspected stroke who underwent WB-CTP. Posterior-circulation-Acute-Stroke-Prognosis-Early-CT-Score (pc-ASPECTS) was determined on noncontrast CT, CT angiography source images, and on parametric WB-CTP maps. Cerebellar perfusion deficit volumes on all maps and the final infarction volume on follow-up imaging were quantified. Uni- and multivariate regression analyses were performed. Sixty patients fulfilled the inclusion criteria. pc-ASPECTS on CT angiography source images (ß, -9.239; 95% CI, -14.220 to -4.259;

Indexed as

Cerebrovascular CirculationComputed Tomography AngiographyTomography, X-Ray ComputedAgedAged, 80 and overBrain IschemiaContrast MediaFemaleHumansMaleMiddle AgedPerfusion ImagingPrognosisRegional Blood FlowStrokeContrast MediaCT perfusion imagingischemic strokeperfusion imagingposterior circulation

Identifiers

PMID31631729
PMCPMC6898835
OpenAlexW2981231922

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.