Evidence map›Paper›PMID 31631242›Full record

ReviewEuropean archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry2019

Guidelines on the use of fluoride for caries prevention in children: an updated EAPD policy document.

K J Toumba, S Twetman, C Splieth, C Parnell, C van Loveren, N Α Lygidakis

Registry-linked trialOpen access · hybridAbstract readReview
PubMed Publisher
In one paragraph

Review in European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06922552 (Clinical Performance of Giomer Preceded by Etching Versus Resin-Based Sealants Applied on Permanent Molars Affected by Molar-Incisor Hypo-mineralization), which is not on this map. Cited by 117 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
117citing papers in PubMed, 6 pooled it
20.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06922552 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Clinical Performance of Giomer Preceded by Etching Versus Resin-Based Sealants Applied on Permanent Molars Affected by Molar-Incisor Hypo-mineralization: A Randomized Clinical Trial

TypeinterventionalSponsorCairo UniversityRan2025 to 2026Enrolled56ConditionsMolar Incisor HypomineralizationArmsGiomer pit and fissure sealant with etching applied on Permanent Molars Affected by MIH, Resin based sealant applied on Permanent Molars Affected by MIH
3 · Its place in the literature

Who cites it

117 citing papers in PubMed, 6 syntheses or guidelines pooled it, 282 citations in OpenAlex.

  1. Pooled it
  2. Guideline
  3. Clinical outcomes of interproximal enamel reduction in orthodontic treatment of children and adolescents: a systematic review.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2025
    Pooled it
  4. Pooled it
  5. Pooled it
  6. Topical fluoride-antibacterial agent combined therapy versus topical fluoride monotherapy in preventing dental caries: a systematic review and meta-analysis.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2020
    Pooled it
  7. Trial
  8. The evaluation of different information methods on behaviour and anxiety levels of children aged 6 to 9 years: a randomised controlled trial.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2025
    Trial
  9. Trial
  10. Trial
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  15. Article
  16. Children's oral health: Are dentists and physicians prepared enough? A cross-sectional interdisciplinary survey carried out in North Italy.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026
    Article
  17. Article
  18. Article
  19. Midwives' knowledge and preventive practices regarding early childhood caries: a quantitative study in France.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026
    Article
  20. Evaluation of the antimicrobial potential of fluoride-free mouthwashes against Scardovia wiggsiae.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026
    Article

57 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 5 countries.

K J ToumbaDevelopmental and Preventive Sciences, Faculty of Dentistry, Kuwait University, Kuwait city, Kuwait. jack.toumba@hsc.edu.kw.ORCID http://orcid.org/0000-0001-8289-4412
S TwetmanDepartment of Odontology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
C SpliethDepartment of Preventive and Paediatric Dentistry, University of Greifswald, Greifswald, Germany.
C ParnellOral Health Services Research Centre and HSE, Louth, Meath, Ireland.
C van LoverenDepartment of Cariology, Academic Centre for Dentistry (ACTA), University of Amsterdam, Amsterdam, The Netherlands.
N Α LygidakisPrivate Paediatric Dental Clinic, 2 Papadiamantopoulou Street, 11528, Athens, Greece.
Academic Center for Dentistry Amsterdam · NLHealth Service Executive · IEKuwait University · KWUniversität Greifswald · DEUniversity of Copenhagen · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo update the exisitng European Academy of Paediatric Dentistry (EAPD) 2009 fluoride guidelines.

methodsExperts met in Athens, Greece duirng November 2018 for the following groups: I Fluoride toothpastes, II Fluoride gels, rinses and varnishes, III Fluoridated milk, fluoridated salt, tablets/lozenges and drops, IV Water fluoridation. Systematic reviews and meta-analyses were reviewed and discussed for each of the groups. The GRADE system was used to assess the quality of evidence which was judged as HIGH, MODERATE, LOW or VERY LOW based on the assessment of eight criteria which can influence the confidence of the results. Following the quality assessment, GRADE was then used to indicate the strength of recommendation for each fluoride agent as STRONG or WEAK/CONDITIONAL.

resultsParents must be strongly advised to apply an age-related amount of toothpaste and assist/supervise tooth brushing until at least 7 years of age. The EAPD strongly endorses the daily use of fluoride as a major part of any comprehensive programme for the prevention and control of dental caries in children. Regardless of the type of programme, community or individually based, the use of fluoride must be balanced between the estimation of caries-risk and the possible risks of adverse effects of the fluorides. Fluoride use is considered safe when the manufacturer's instructions are followed. Preventive programmes should be re-evaluated at regular intervals and adapted to a patient's or population's needs and risks.

conclusionsFor the majority of European Countries, the EAPD recommends the appropriate use of fluoride toothpaste in conjunction with good oral hygiene to be the basic fluoride regimen.

Indexed as

Dental CariesFluoridesAnimalsCariostatic AgentsChildEuropeGreeceHumansPediatric DentistryToothpastesCariostatic AgentsFluoridesToothpastesCariesChildFluoride

Identifiers

PMID31631242
OpenAlexW2980426141

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.