Evidence map›Paper›PMID 31631076›Full record

ArticleAnnals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia2020

Administration of Corticosteroids, Ascorbic Acid, and Thiamine Improves Oxygenation after Thoracoscopic Esophagectomy.

Tadashi Matsuoka, Hiroharu Shinozaki, Soji Ozawa, Yoshimitsu Izawa, Kazuo Koyanagi, Alan Kawarai Lefor, Kenji Kobayashi

Open access · goldAbstract read
In one paragraph

Article in Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Copper and zinc dynamics in ovine pneumonia: a comparative analysis of treatment regimens.Veterinary research forum : an international quarterly journal · 2025
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Tadashi MatsuokaDepartment of Surgery, Saiseikai Utsunomiya Hospital, Utsunomiya, Tochigi, Japan.
Hiroharu ShinozakiDepartment of Surgery, Saiseikai Utsunomiya Hospital, Utsunomiya, Tochigi, Japan.
Soji OzawaDepartment of Gastroenterological Surgery, School of Medicine, Tokai University, Isehara, Kanagawa, Japan.
Yoshimitsu IzawaDepartment of Surgery, Saiseikai Utsunomiya Hospital, Utsunomiya, Tochigi, Japan.
Kazuo KoyanagiDepartment of Gastroenterological Surgery, School of Medicine, Tokai University, Isehara, Kanagawa, Japan.
Alan Kawarai LeforDepartment of Surgery, Jichi Medical University, Shimotsuke, Tochigi, Japan.
Kenji KobayashiDepartment of Surgery, Saiseikai Utsunomiya Hospital, Utsunomiya, Tochigi, Japan.
Saiseikai Utsunomiya hospital · JPTokai University · JPJichi Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe activity of corticosteroids, ascorbic acid, and thiamine against oxidative and inflammatory responses was evaluated in patients undergoing esophagectomy. This study was undertaken to investigate the effect of this combined therapy on lung dysfunction following esophagectomy.

methodsIn this retrospective before-after study, we compared the clinical course of consecutive patients undergoing thoracoscopic esophagectomy treated with the combination of corticosteroids, ascorbic acid, and thiamine between June and December 2018 with a control group treated with corticosteroids alone between January 2016 and May 2018. Outcomes included oxygenation (arterial partial pressure of oxygen (PaO

resultsIn all, 17 patients were included in this study (6 in the combination therapy group and 11 patients in the control group). Mean PaO

conclusionsThis study suggests that combined therapy including corticosteroids, ascorbic acid, and thiamine may be effective in improving oxygenation after esophagectomy. Additional studies are required to confirm these preliminary findings.

Indexed as

ThoracoscopyAdrenal Cortex HormonesAgedAscorbic AcidBiomarkersEsophagectomyFemaleHumansIntensive Care UnitsLength of StayLungLung InjuryMaleOxygenPilot ProjectsRespiration, ArtificialAdrenal Cortex HormonesAscorbic AcidBiomarkersOxygenThiamineascorbic acidcorticosteroidsesophagectomylung injury

Identifiers

PMID31631076
PMCPMC7303314
OpenAlexW2980513130

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.