Evidence map›Paper›PMID 31630575›Full record

ArticleHypertension (Dallas, Tex. : 1979)2019

Opposing Age-Related Trends in Absolute and Relative Risk of Adverse Health Outcomes Associated With Out-of-Office Blood Pressure.

Yan Li, Lutgarde Thijs, Zhen-Yu Zhang, Kei Asayama, Tine W Hansen, José Boggia, Kristina Björklund-Bodegård, Wen-Yi Yang, Teemu J Niiranen, Angeliki Ntineri and 31 more

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Hypertension (Dallas, Tex. : 1979), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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  11. [Blood pressure patterns in pressurometry and their ralationship with cardiovascular events in follow-up]Revista de la Facultad de Ciencias Medicas (Cordoba, Argentina) · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

41 authors.

Yan LiCenter for Epidemiological Studies and Clinical Trials and Center for Vascular Evaluations, Shanghai Institute of Hypertension, Shanghai Key Laboratory of Hypertension, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, China (Y.L., Q.-F.H., J.-G.W.).
Lutgarde ThijsResearch Unit Hypertension and Cardiovascular Epidemiology, KU Leuven Department of Cardiovascular Sciences, University of Leuven, Belgium (L.T., Z.-Y.Z., W.-Y.Y., F.-F.W., T.K., J.A.S.).
Zhen-Yu ZhangResearch Unit Hypertension and Cardiovascular Epidemiology, KU Leuven Department of Cardiovascular Sciences, University of Leuven, Belgium (L.T., Z.-Y.Z., W.-Y.Y., F.-F.W., T.K., J.A.S.).
Kei AsayamaDepartment of Hygiene and Public Health, Teikyo University School of Medicine, Tokyo, Japan (K.A., M.K., T.O.).
Tine W HansenSteno Diabetes Center Copenhagen, Gentofte, and Research Centre for Prevention and Health, Capital Region of Denmark, Denmark (T.W.H.).
José BoggiaCentro de Nefrología and Departamento de Fisiopatología, Hospital de Clínicas, Universidad de la República, Montevideo, Uruguay (J.B.).
Kristina Björklund-BodegårdDivision of Cardiovascular Medicine, Department of Clinical Sciences, Danderyd Hospital, Karolinska Institutet, Stockholm, Sweden (K.B.B.).
Wen-Yi YangResearch Unit Hypertension and Cardiovascular Epidemiology, KU Leuven Department of Cardiovascular Sciences, University of Leuven, Belgium (L.T., Z.-Y.Z., W.-Y.Y., F.-F.W., T.K., J.A.S.).
Teemu J NiiranenNational Institute for Health and Welfare, Turku, Finland (T.J.N., A.M.J., J.K.J.).
Angeliki NtineriHypertension Center STRIDE-7, National and Kapodistrian University of Athens, School of Medicine, Third Department of Medicine, Sotiria Hospital, Greece (A.N., G.S.).
Fang-Fei WeiResearch Unit Hypertension and Cardiovascular Epidemiology, KU Leuven Department of Cardiovascular Sciences, University of Leuven, Belgium (L.T., Z.-Y.Z., W.-Y.Y., F.-F.W., T.K., J.A.S.).
Masahiro KikuyaDepartment of Hygiene and Public Health, Teikyo University School of Medicine, Tokyo, Japan (K.A., M.K., T.O.).
Takayoshi OhkuboDepartment of Hygiene and Public Health, Teikyo University School of Medicine, Tokyo, Japan (K.A., M.K., T.O.).
Eamon DolanStroke and Hypertension Unit, Blanchardstown, Dublin, Ireland (E.D.).
Atsushi HozawaDepartment of Preventive Medicine and Epidemiology, Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan (A.H.).
Ichiro TsujiDepartment of Public Health, Tohoku University Graduate School of Medicine, Sendai, Japan (I.T.).
Katarzyna Stolarz-SkrzypekFirst Department of Cardiology, Interventional Electrocardiology and Hypertension, Jagiellonian University Medical College, Kraków, Poland (K.S.-S., K.K.J.).
Qi-Fang HuangCenter for Epidemiological Studies and Clinical Trials and Center for Vascular Evaluations, Shanghai Institute of Hypertension, Shanghai Key Laboratory of Hypertension, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, China (Y.L., Q.-F.H., J.-G.W.).
Jesus D MelgarejoLaboratorio de Neurociencias and Instituto Cardiovascular, Universidad del Zulia, Maracaibo, Venezuela (J.D.M.-A., G.E.M).
Valérie TikhonoffDepartment of Medicine, University of Padova, Italy (V.T., E.C.).
Sofia MalyutinaInstitute of Internal and Preventive Medicine, Internal and Preventive Medicine - Branch of the Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Science, Novosibirsk, Russian Federation (S.M., Y.N.).
Edoardo CasigliaDepartment of Medicine, University of Padova, Italy (V.T., E.C.).
Yuri NikitinInstitute of Internal and Preventive Medicine, Internal and Preventive Medicine - Branch of the Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Science, Novosibirsk, Russian Federation (S.M., Y.N.).
Lars LindDepartment of Public Health and Caring Sciences, Section of Geriatrics, Uppsala University, Sweden (L.L.).
Edgardo SandoyaAsociación Española Primera de Socorros Mutuos, Montevideo, Uruguay (E.S.).
Lucas AparicioDepartment of Medicine, Hospital Italiano de Buenos Aires, University of Buenos Aires, Argentina (L.A., J.B.).
Jessica BarochinerDepartment of Medicine, Hospital Italiano de Buenos Aires, University of Buenos Aires, Argentina (L.A., J.B.).
Natasza Gilis-MalinowskaDepartment of Hypertension, Medical University of Gdańsk, Poland (N.G.M., K.N.).
Krzysztof NarkiewiczDepartment of Hypertension, Medical University of Gdańsk, Poland (N.G.M., K.N.).
Kalina Kawecka-JaszczFirst Department of Cardiology, Interventional Electrocardiology and Hypertension, Jagiellonian University Medical College, Kraków, Poland (K.S.-S., K.K.J.).
Gladys E MaestreLaboratorio de Neurociencias and Instituto Cardiovascular, Universidad del Zulia, Maracaibo, Venezuela (J.D.M.-A., G.E.M).
Antti M JulaNational Institute for Health and Welfare, Turku, Finland (T.J.N., A.M.J., J.K.J.).
Jouni K JohanssonNational Institute for Health and Welfare, Turku, Finland (T.J.N., A.M.J., J.K.J.).
Tatiana KuznetsovaResearch Unit Hypertension and Cardiovascular Epidemiology, KU Leuven Department of Cardiovascular Sciences, University of Leuven, Belgium (L.T., Z.-Y.Z., W.-Y.Y., F.-F.W., T.K., J.A.S.).
Jan FilipovskýFaculty of Medicine, Charles University, Pilsen, Czech Republic (J.F.).
George StergiouHypertension Center STRIDE-7, National and Kapodistrian University of Athens, School of Medicine, Third Department of Medicine, Sotiria Hospital, Greece (A.N., G.S.).
Ji-Guang WangCenter for Epidemiological Studies and Clinical Trials and Center for Vascular Evaluations, Shanghai Institute of Hypertension, Shanghai Key Laboratory of Hypertension, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, China (Y.L., Q.-F.H., J.-G.W.).
Yutaka ImaiDepartment of Hygiene and Public Health, Teikyo University School of Medicine, Tokyo, Japan (K.A., M.K., T.O.).
Eoin O'BrienConway Institute, University College Dublin, Ireland (E.O.B.).
Jan A StaessenResearch Unit Hypertension and Cardiovascular Epidemiology, KU Leuven Department of Cardiovascular Sciences, University of Leuven, Belgium (L.T., Z.-Y.Z., W.-Y.Y., F.-F.W., T.K., J.A.S.).
International Database on Ambulatory and Home Blood Pressure in Relation to Cardiovascular Outcome Investigators

Funding

South Texas Alzheimer's Disease Research CenterP30AG066546 · NIA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI Mohamad Habes · 2021 to 2026
$24.0M
Gene-Environment Interactions in Cognition in Venezuelan FamiliesR01AG036469 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI CHACON, INARA, MAESTRE, GLADYS E. · 2011 to 2015
$2.7M
A longitudinal study of mid-to late-life blood pressure profiles as risk factors for Alzheimer´s disease in HispanicsR03AG054186 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MAESTRE, GLADYS E., TERWILLIGER, JOSEPH DOUGLAS · 2016 to 2017
$163k
NIA NIH HHS P30 AG066546NIA NIH HHS R01 AG036469NIA NIH HHS R03 AG054186
6 · The paper itself

Abstract

Participant-level meta-analyses assessed the age-specific relevance of office blood pressure to cardiovascular complications, but this information is lacking for out-of-office blood pressure. At baseline, daytime ambulatory (n=12 624) or home (n=5297) blood pressure were measured in 17 921 participants (51.3% women; mean age, 54.2 years) from 17 population cohorts. Subsequently, mortality and cardiovascular events were recorded. Using multivariable Cox regression, floating absolute risk was computed across 4 age bands (≤60, 61-70, 71-80, and >80 years). Over 236 491 person-years, 3855 people died and 2942 cardiovascular events occurred. From levels as low as 110/65 mm Hg, risk log-linearly increased with higher out-of-office systolic/diastolic blood pressure. From the youngest to the oldest age group, rates expressed per 1000 person-years increased (

Indexed as

Blood Pressure DeterminationCardiovascular DiseasesHypertensionSelf-ManagementAgedAge FactorsBlood Pressure Monitoring, AmbulatoryCohort StudiesFemaleHealth StatusHumansInternationalityMaleMiddle AgedMultivariate AnalysisOffice Visitsambulatoryblood pressureblood pressure monitoringcardiovascular diseaseshypertensionmortality

Identifiers

PMID31630575
PMCPMC6854319

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.