Evidence map›Paper›PMID 31630546›Full record

ArticleAmerican journal of physiology. Renal physiology2019

Differential expression of parietal epithelial cell and podocyte extracellular matrix proteins in focal segmental glomerulosclerosis and diabetic nephropathy.

Gek Cher Chan, Diana G Eng, Jeffrey H Miner, Charles E Alpers, Kelly Hudkins, Anthony Chang, Jeffrey W Pippin, Stuart J Shankland

Open access · bronzeAbstract read
In one paragraph

Article in American journal of physiology. Renal physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 38 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Gek Cher ChanDivision of Nephrology, University of Washington, Seattle, Washington.ORCID 0000-0002-4661-3350
Diana G EngDivision of Nephrology, University of Washington, Seattle, Washington.
Jeffrey H MinerDivision of Nephrology, Washington University School of Medicine, St. Louis, Missouri.ORCID 0000-0002-1510-8714
Charles E AlpersDepartment of Pathology, University of Washington, Seattle, Washington.
Kelly HudkinsDepartment of Pathology, University of Washington, Seattle, Washington.
Anthony ChangDepartment of Pathology, University of Chicago, Chicago, Illinois.ORCID 0000-0002-6877-5510
Jeffrey W PippinDivision of Nephrology, University of Washington, Seattle, Washington.
Stuart J ShanklandDivision of Nephrology, University of Washington, Seattle, Washington.
University of Washington · USUniversity of Chicago · USWashington University in St. Louis · US

Funding

Vector and Transgenic Mouse CoreP30DK017047 · NIDDK · UNIVERSITY OF WASHINGTON · PI Karin E Bornfeldt · 1986 to 2026
$41.4M
STRUCTURE AND FUNCTION OF CD2AP IN THE KIDNEYR01DK058366 · NIDDK · WASHINGTON UNIVERSITY · PI MINER, JEFFREY H · 2000 to 2019
$6.8M
LAMININS AND GLOMERULAR FILTRATIONR01DK078314 · NIDDK · WASHINGTON UNIVERSITY · PI MINER, JEFFREY H · 2008 to 2021
$5.4M
Juxta-glomerular cells serve as glomerular epithelial cell progenitors in glomerular diseaseR01DK097598 · NIDDK · UNIVERSITY OF WASHINGTON · PI SHANKLAND, STUART JAMES, WESSELY, OLIVER · 2014 to 2022
$5.2M
CELL CYCLE PROTEINS AND GLOMERULAR APOPTOSISR01DK056799 · NIDDK · UNIVERSITY OF WASHINGTON · PI SHANKLAND, STUART JAMES · 2000 to 2014
$3.6M
NIDDK NIH HHS P30 DK017047NIDDK NIH HHS R01 DK056799NIDDK NIH HHS R01 DK058366NIDDK NIH HHS R01 DK078314NIDDK NIH HHS R01 DK097598
6 · The paper itself

Abstract

In healthy glomeruli, parietal epithelial cell (PEC)-derived extracellular matrix (ECM) proteins include laminin-β

Indexed as

AgrinAnimalsCollagen Type IVDiabetic NephropathiesEpithelial CellsExtracellular Matrix ProteinsGlomerulosclerosis, Focal SegmentalHumansHyaluronan ReceptorsKidneyLamininMaleMiceMice, KnockoutMice, ObesePodocytesAgrinCOL4A4 protein, humanCollagen Type IVExtracellular Matrix ProteinsHyaluronan ReceptorsLamininlaminin beta2CD44extracellular matrix proteinglomerular diseaseparietal epithelial cellpodocyte

Identifiers

PMID31630546
PMCPMC6962515
OpenAlexW2981055214

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.