ArticleBiomechanics and modeling in mechanobiology2020
An orthotropic electro-viscoelastic model for the heart with stress-assisted diffusion.
Article in Biomechanics and modeling in mechanobiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 22 citations in OpenAlex.
- On the second gradient nonlinear spectral constitutive modelling of viscoelastic composites reinforced with stiff fibers.Scientific reports · 2025Article
- Proposed cardio-pulmonary model to investigate the effects of COVID-19 on the cardiovascular system.Heliyon · 2023Article
- Strain-dependent stress relaxation behavior of healthy right ventricular free wall.Acta biomaterialia · 2022Article
- Precision medicine in human heart modeling : Perspectives, challenges, and opportunities.Biomechanics and modeling in mechanobiology · 2021Review
- Shear wave speeds in nearly-incompressible fibrous materials with two fiber families.The Journal of the Acoustical Society of America · 2021Article
- Sensitivity analysis of a strongly-coupled human-based electromechanical cardiac model: Effect of mechanical parameters on physiologically relevant biomarkers.Computer methods in applied mechanics and engineering · 2020Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 4 countries.
Funding
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Abstract
We propose and analyse the properties of a new class of models for the electromechanics of cardiac tissue. The set of governing equations consists of nonlinear elasticity using a viscoelastic and orthotropic exponential constitutive law, for both active stress and active strain formulations of active mechanics, coupled with a four-variable phenomenological model for human cardiac cell electrophysiology, which produces an accurate description of the action potential. The conductivities in the model of electric propagation are modified according to stress, inducing an additional degree of nonlinearity and anisotropy in the coupling mechanisms, and the activation model assumes a simplified stretch-calcium interaction generating active tension or active strain. The influence of the new terms in the electromechanical model is evaluated through a sensitivity analysis, and we provide numerical validation through a set of computational tests using a novel mixed-primal finite element scheme.
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Registered trials
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