Evidence map›Paper›PMID 31630114›Full record

ReviewThe Journal of neuroscience : the official journal of the Society for Neuroscience2020

Of Molecules and Mechanisms.

Deanna L Benson

Abstract readHistorical ArticleReview
In one paragraph

Review in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Pipette Olympics: An Engaging Exercise for Undergraduate Laboratory Training.Journal of undergraduate neuroscience education : JUNE : a publication of FUN, Faculty for Undergraduate Neuroscience · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Deanna L BensonNash Family Department of Neuroscience and Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029 deanna.benson@mssm.edu.ORCID 0000-0001-7037-1147

Funding

Developmentally sensitive regulatory mechanisms of synapse assembly and functionR01MH103455 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI BENSON, DEANNA L, GUNAL, OZLEM · 2014 to 2018
$2.1M
Impact of human disease-causing mutation on striatal synaptic and behavioral plasticityR01NS107512 · NINDS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI BENSON, DEANNA L, HUNTLEY, GEORGE W. · 2019 to 2022
$2.1M
Cdh8-dependent circuit development in autismR01MH104491 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI BENSON, DEANNA L, HUNTLEY, GEORGE W. · 2016 to 2020
$1.9M
NIMH NIH HHS R01 MH103455NIMH NIH HHS R01 MH104491NINDS NIH HHS R01 NS107512
6 · The paper itself

Abstract

Without question, molecular biology drives modern neuroscience. The past 50 years has been nothing short of revolutionary as key findings have moved the field from correlation toward causation. Most obvious are the discoveries and strategies that have been used to build tools for visualizing circuits, measuring activity, and regulating behavior. Less flashy, but arguably as important are the myriad investigations uncovering the actions of single molecules, macromolecular structures, and integrated machines that serve as the basis for constructing cellular and signaling pathways identified in wide-scale gene or RNA studies and for feeding data into informational networks used in systems biology. This review follows the pathways that were opened in neuroscience by major discoveries and set the stage for the next 50 years.

Indexed as

AnimalsCRISPR-Cas SystemsExocytosisGene Expression RegulationGenes, ReporterGene Transfer TechniquesHistory, 20th CenturyHistory, 21st CenturyHumansIn Situ HybridizationMicroscopyMolecular BiologyNerve Tissue ProteinsNeurosciencesPDZ DomainsPolymerase Chain ReactionNerve Tissue ProteinsRecombinant ProteinsRNACRISPR-Cas9nanoscale imagingPCRRNASNARE and synapse compositiontransfection and transduction

Identifiers

PMID31630114
PMCPMC6939483

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.