Thermally stable and uniform DNA amplification with picosecond laser ablated graphene rapid thermal cycling device.

Zhao-Chi Chen, Tien-Li Chang, Ching-Hao Li, Kai-Wen Su, Cheng-Che Liu

Abstract read

In one paragraph

Article in Biosensors & bioelectronics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Artefact Profiling: Panomics Approaches for Understanding the Materiality of Written Artefacts.Molecules (Basel, Switzerland) · 2023
Review

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zhao-Chi ChenDepartment of Mechatronic Engineering, National Taiwan Normal University, Taipei, Taiwan, ROC.

Tien-Li ChangDepartment of Mechatronic Engineering, National Taiwan Normal University, Taipei, Taiwan, ROC. Electronic address: tlchang@ntnu.edu.tw.

Ching-Hao LiDepartment of Physiology, School of Medicine, Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei, Taiwan, ROC.

Kai-Wen SuIntegrated Science, University of British Columbia, Columbia, Canada.

Cheng-Che LiuGraduate Institute of Physiology, National Defense Medical Center, Taipei, Taiwan, ROC. Electronic address: jasonliu@mail.ndmctsgh.edu.tw.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rapid thermal cycling (RTC) in an on-chip device can perform DNA amplification in vitro through precise thermal control at each step of the polymerase chain reaction (PCR). This study reports a straightforward fabrication technique for patterning an on-chip graphene-based device with hole arrays, in which the mechanism of surface structures can achieve stable and uniform thermal control for the amplification of DNA fragments. A thin-film based PCR device was fabricated using picosecond laser (PS-laser) ablation of the multilayer graphene (MLG). Under the optimal fluence of 4.72 J/cm

Indexed as

BK VirusDNADNA, ViralEquipment DesignGraphiteHumansLasersPolymerase Chain ReactionPolyomavirus InfectionsTemperatureTumor Virus InfectionsDNADNA, ViralGraphiteDNA amplificationGraphenePCR devicePicosecond laser ablationThermal stability and uniformityThin-film device

Identifiers

PMID31629228

DOI10.1016/j.bios.2019.111581

PMCPMC7126615

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.