Evidence map›Paper›PMID 31629093›Full record

ArticlePapillomavirus research (Amsterdam, Netherlands)2019

Association of human papillomavirus related squamous cell carcinomas of the oropharynx and cervix.

Malak Jamal Gazzaz, Caroline Jeffery, Daniel O'Connell, Jeffery Harris, Hadi Seikaly, Vincent Biron

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Papillomavirus research (Amsterdam, Netherlands), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Malak Jamal GazzazDivision of Otolaryngology-Head & Neck Surgery, University of Alberta Hospital, 1E4, Walter Mackenzie Centre, 8440-112 Street, Edmonton, AB, T6G 2B7, Canada. Electronic address: mgazzaz@ualberta.ca.
Caroline JefferyDivision of Otolaryngology-Head & Neck Surgery, University of Alberta Hospital, 1E4, Walter Mackenzie Centre, 8440-112 Street, Edmonton, AB, T6G 2B7, Canada. Electronic address: caroline.jeffery@albertahealthservices.ca.
Daniel O'ConnellDivision of Otolaryngology-Head & Neck Surgery, University of Alberta Hospital, 1E4, Walter Mackenzie Centre, 8440-112 Street, Edmonton, AB, T6G 2B7, Canada. Electronic address: dan.oconnell@ualberta.ca.
Jeffery HarrisDivision of Otolaryngology-Head & Neck Surgery, University of Alberta Hospital, 1E4, Walter Mackenzie Centre, 8440-112 Street, Edmonton, AB, T6G 2B7, Canada. Electronic address: jeffrey.harris@albertahealthservices.ca.
Hadi SeikalyDivision of Otolaryngology-Head & Neck Surgery, University of Alberta Hospital, 1E4, Walter Mackenzie Centre, 8440-112 Street, Edmonton, AB, T6G 2B7, Canada. Electronic address: hadi.seikaly@albertahealthservices.ca.
Vincent BironDivision of Otolaryngology-Head & Neck Surgery, University of Alberta Hospital, 1E4, Walter Mackenzie Centre, 8440-112 Street, Edmonton, AB, T6G 2B7, Canada; Otolaryngology Head and Neck Surgery Research Lab of Alberta (OHRLA), 3-125 Li Ka Shing Centre for Health Research Innovation, 8602 112 Street, Edmonton, AB, Canada. Electronic address: vbiron@ualberta.ca.
University of Alberta Hospital · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHuman Papillomavirus (HPV) infection is well established in oropharyngeal squamous cell carcinoma (OPSCC) and cervical cancer (CC). However, the association between both HPV related cancers remains unclear. The purpose of this study was to investigate the association between HPV related cancers of the oropharynx and cervix.

methodsA provincial cancer registry was used to retrospectively identify all patients diagnosed with OPSCC from 1997-2015. The standardized incidence ratio (SIR) of CC history in women with p16+/-OPSCC was measured.

resultsFrom 372 women with OPSCC included, the SIR of CC was significantly higher across all ages compared to the general population in Alberta, Canada (p < 0.0001).

conclusionsWomen with HPV/p16+ OPSCC have a significantly higher risk of CC compared to the general population.

Indexed as

AdultAgedAged, 80 and overAge FactorsAlbertaCarcinoma, Squamous CellCell Transformation, ViralDisease SusceptibilityFemaleHumansIncidenceMaleMiddle AgedNeoplasm GradingNeoplasm StagingOropharyngeal NeoplasmsCervical cancerHuman papillomavirusOropharyngeal cancerp16

Identifiers

PMID31629093
PMCPMC6818328
OpenAlexW2980537682

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.