ArticleThe international journal of cardiovascular imaging2020
On-site evaluation of CT-based fractional flow reserve using simple boundary conditions for computational fluid dynamics.
Article in The international journal of cardiovascular imaging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Device-Oriented CFD Comparison of Rectangular and Circular Microchannels with Single and Double Asymmetric Stenoses Under Identical Operating Conditions.Bioengineering (Basel, Switzerland) · 2025Article
- Maximum admittance method for cerebrovascular outlet boundary conditions and importance of stenosis severity as a dominant factor on hemodynamics.Scientific reports · 2025Article
- A novel physics-based model for fast computation of blood flow in coronary arteries.Biomedical engineering online · 2023Article
- Fractional Flow Reserve (FFR) Estimation from OCT-Based CFD Simulations: Role of Side Branches.Applied sciences (Basel, Switzerland) · 2022Article
- A phantom and in vivo simulation of coronary flow to calculate fractional flow reserve using a mesh-free model.The international journal of cardiovascular imaging · 2022Article
- Functional cardiac CT-Going beyond Anatomical Evaluation of Coronary Artery Disease with Cine CT, CT-FFR, CT Perfusion and Machine Learning.The British journal of radiology · 2020Review
- Cardiovascular imaging 2019 in the International Journal of Cardiovascular Imaging.The international journal of cardiovascular imaging · 2020Article
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fractional flow reserve (FFR) is an established method for diagnosing physiological coronary artery stenosis. A method for computing FFR using coronary computed tomography (CT) images was recently developed. However, its calculation requires off-site supercomputer analysis. Here, we report the preliminary result of a method using simple estimation of boundary conditions. The lumen boundaries of the coronary arteries were semi-automatically delineated using full width at half maximum of CT number profiles. The computational fluid dynamics (CFD) of the blood flow was performed using the boundary conditions of a fixed pressure at the coronary ostium and flow rates at each outlet. The total inflow at the coronary ostium was estimated based on the uniform wall shear stress hypothesis and corrected using a hyperemic multiplier to gain a hyperemic flow rate. The flow distribution from a parent vessel to the downstream daughter vessels was determined according to Murray's law. FFR estimated by CFD was calculated as FFR
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