Evidence map›Paper›PMID 31628427›Full record

ArticleMucosal immunology2020

MicroRNA-219a-5p suppresses intestinal inflammation through inhibiting Th1/Th17-mediated immune responses in inflammatory bowel disease.

Yan Shi, Shenglan Dai, Caiyu Qiu, Tao Wang, Yong Zhou, Cuihua Xue, Jun Yao, Yaping Xu

Open access · bronzeAbstract read
PubMed Publisher
In one paragraph

Article in Mucosal immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 43 citations in OpenAlex.

  1. Article
  2. Article
  3. The Role of microRNAs in Inflammatory Bowel Disease.International journal of molecular sciences · 2025
    Review
  4. Review
  5. Article
  6. ETS Transcription Factors in Immune Cells and Immune-Related Diseases.International journal of molecular sciences · 2024
    Review
  7. Article
  8. Review
  9. Review
  10. MicroRNAs in T Cell-Immunotherapy.International journal of molecular sciences · 2022
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. MicroRNA-10a Negatively Regulates CD4Journal of immunology (Baltimore, Md. : 1950) · 2021
    Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Yan ShiDepartment of Gastroenterology, Affiliated People's Hospital of Jiangsu University, Zhenjiang, 212002, China.
Shenglan DaiDepartment of Gastroenterology, Affiliated People's Hospital of Jiangsu University, Zhenjiang, 212002, China.
Caiyu QiuDepartment of Gastroenterology, Affiliated People's Hospital of Jiangsu University, Zhenjiang, 212002, China.
Tao WangDepartment of Gastroenterology, Affiliated People's Hospital of Jiangsu University, Zhenjiang, 212002, China.
Yong ZhouDepartment of Gastroenterology, Affiliated People's Hospital of Jiangsu University, Zhenjiang, 212002, China.
Cuihua XueDepartment of Gastroenterology, Affiliated People's Hospital of Jiangsu University, Zhenjiang, 212002, China.
Jun YaoDepartment of Gastroenterology, Affiliated People's Hospital of Jiangsu University, Zhenjiang, 212002, China. YaojunYRY@163.com.
Yaping XuDepartment of Gastroenterology, Affiliated People's Hospital of Jiangsu University, Zhenjiang, 212002, China. xyp1201@163.com.
Jiangsu University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MicroRNA (miR)-219a-5p has been implicated in the development of numerous progression of carcinoma and autoimmune diseases. However, whether miR-219a-5p is involved in the pathogenesis of inflammatory bowel disease (IBD) remains elusive. In this study, we demonstrated that miR-219a-5p expression was significantly decreased in the inflamed intestinal mucosa and peripheral blood (PB)-CD4

Indexed as

AdultAnimalsCells, CulturedColitisDisease Models, AnimalDNA-Binding ProteinsFemaleGene Expression RegulationHumansInflammatory Bowel DiseasesMaleMiceMice, Inbred BALB CMicroRNAsMiddle AgedTh17 CellsDNA-Binding ProteinsETV5 protein, humanMicroRNAsMIRN219 microRNA, mouseTranscription FactorsTrinitrobenzenesulfonic Acid

Identifiers

PMID31628427
OpenAlexW2980554132

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.