ArticleNature communications2019
Puma genomes from North and South America provide insights into the genomic consequences of inbreeding.
Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 56 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
56 citing papers in PubMed, 140 citations in OpenAlex.
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- Checklist and Review of Population Genetic Studies with Molecular Markers Applied to the Wild Cat Species Present in Colombia for Conservation Purposes.Animals : an open access journal from MDPI · 2026Review
- From individuals to communities: How genomics is transforming biodiversity conservation.Genetics and molecular biology · 2026Article
- Improved Bayesian inference of hybrids using genome sequences.bioRxiv : the preprint server for biology · 2025Article
- Genomic Signatures in Maned Three-Toed Sloths From Ancient to Recent Environmental Changes in Brazil's Threatened Atlantic Forest.Molecular ecology · 2025Article
- Genome Variation in Three Anthophora Bee Species Reflects Divergent Demographic Histories.Molecular ecology · 2025Article
- Admixture Increases Genetic Diversity and Adaptive Potential in Australasian Killer Whales.Molecular ecology · 2025Article
- Unraveling the Genetic Diversity of Asian Elephants (Ecology and evolution · 2025Article
- Characterisation of the Historic Demographic Decline of the British European Polecat Population.Molecular ecology · 2025Article
- Genetic rescue of Florida panthers reduced homozygosity but did not swamp ancestral genotypes.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- A chromosome-level genome assembly of the mountain lion, Puma concolor.The Journal of heredity · 2025Article
- Linking Measures of Inbreeding and Genetic Load to Demographic Histories Across Three Species of Bears.Evolutionary applications · 2025Article
- Natural dispersal is better than translocation for reducing risks of inbreeding depression in eastern black rhinoceros (Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Methylation-associated mutagenesis underlies variation in the mutation spectrum across eukaryotes.bioRxiv : the preprint server for biology · 2025Article
- Genomic insights and the conservation potential of captive breeding: The case of Chinese alligator.Science advances · 2025Article
Corrections and comments
- Erratum issued
Authors and funding
23 authors at 11 institutions in 4 countries.
Funding
Abstract
Pumas are the most widely distributed felid in the Western Hemisphere. Increasingly, however, human persecution and habitat loss are isolating puma populations. To explore the genomic consequences of this isolation, we assemble a draft puma genome and a geographically broad panel of resequenced individuals. We estimate that the lineage leading to present-day North American pumas diverged from South American lineages 300-100 thousand years ago. We find signatures of close inbreeding in geographically isolated North American populations, but also that tracts of homozygosity are rarely shared among these populations, suggesting that assisted gene flow would restore local genetic diversity. The genome of a Florida panther descended from translocated Central American individuals has long tracts of homozygosity despite recent outbreeding. This suggests that while translocations may introduce diversity, sustaining diversity in small and isolated populations will require either repeated translocations or restoration of landscape connectivity. Our approach provides a framework for genome-wide analyses that can be applied to the management of similarly small and isolated populations.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.