ArticleItalian journal of pediatrics2019
Kawasaki disease triggered by EBV virus in a child with Familial Mediterranean Fever.
Article in Italian journal of pediatrics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 18 citations in OpenAlex.
- Infectious mononucleosis complicated with Kawasaki disease: Two case reports and literature review.Pediatric investigation · 2025Article
- Cardiovascular involvement in children with COVID-19 temporally related multisystem inflammatory syndrome (MIS-C): can cardiac magnetic resonance arrive to the heart of the problem?Italian journal of pediatrics · 2024Article
- Emerging evidence of microbial infection in causing systematic immune vasculitis in Kawasaki disease.Frontiers in microbiology · 2023Review
- Two Distinct Cases of Adult-onset Kawasaki Disease.Internal medicine (Tokyo, Japan) · 2022Article
- Multisystem Inflammatory Syndrome with Features of Atypical Kawasaki Disease during the COVID-19 Pandemic.Case reports in pediatrics · 2021Article
- Coronary artery bypass grafting in children for atheromatous and non-atheromatous lesions.Indian journal of thoracic and cardiovascular surgery · 2021Article
- Differentially expressed genes, lncRNAs, and competing endogenous RNAs in Kawasaki disease.PeerJ · 2021Article
- Kawasaki Disease as the Immune-Mediated Echo of a Viral Infection.Mediterranean journal of hematology and infectious diseases · 2020Review
- COVID-19 in Children: A Review and Parallels to Other Hyperinflammatory Syndromes.Frontiers in pediatrics · 2020Review
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFamilial Mediterranean Fever is a monogenic autoinflammatory disease, secondary to mutation of MEFV gene, and typically expressed with recurrent attacks of fever, serositis, rash, aphthous changes in lips and/or oral mucosa. Kawasaki Disease, an acute systemic vasculitis with persistent fever (5 or more days), rash, stomatitis, conjunctivitis, lymphadenopathy, changes in extremities, is currently considered a multifactorial autoinflammatory disease. An infection, as Epstein Barr virus, can be the trigger of Kawasaki Disease. CASE PRESENTATION: We describe the clinical case of a 3-year-old boy with Kawasaki disease. Successfully treated with intravenous immune globulin, acetyl salicylate acid, he late developed anaemia and thrombocytopenia. The Epstein-Barr virus infection has been demonstrated and he showed a resolution of the clinical manifestations of Kawasaki disease with the persistence of coronaritis, without aneurisms. However, for the personal and familial history of monthly recurrent attacks of fever, pharyngitis, abdominal pain, the genetic study of MEFV was performed and demonstrated 3 heterozygous mutations of MEFV (E148Q, P369S, R408Q).
conclusionsMutations of MEFV can contribute to increase inflammatory expression in other diseases, as Kawasaki disease.
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