Evidence map›Paper›PMID 31627428›Full record

ArticleInternational journal of molecular sciences2019

ALS-Associated SOD1(G93A) Decreases SERCA Pump Levels and Increases Store-Operated Ca

Rosa Pia Norante, Caterina Peggion, Daniela Rossi, Francesca Martorana, Agnese De Mario, Annamaria Lia, Maria Lina Massimino, Alessandro Bertoli

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Rosa Pia NoranteDepartment of Biomedical Sciences, University of Padova, 35131 Padova, Italy. rosa.norante@gmail.com.
Caterina PeggionDepartment of Biomedical Sciences, University of Padova, 35131 Padova, Italy. catpeg@outlook.it.
Daniela RossiLaboratory for Research on Neurodegenerative Disorders, Istituti Clinici Scientifici Maugeri SpA SB-IRCCS, 27100 Pavia, Italy. daniela.rossi@icsmaugeri.it.
Francesca MartoranaLaboratory for Research on Neurodegenerative Disorders, Istituti Clinici Scientifici Maugeri SpA SB-IRCCS, 27100 Pavia, Italy. francesca.martorana@icsmaugeri.it.
Agnese De MarioDepartment of Biomedical Sciences, University of Padova, 35131 Padova, Italy. agnese.demario@unipd.it.
Annamaria LiaDepartment of Biomedical Sciences, University of Padova, 35131 Padova, Italy. annamaria.lia@unipd.it.
Maria Lina MassiminoCNR-Neuroscience Institute, University of Padova, 35131 Padova, Italy. marilina.massimino@gmail.com.
Alessandro BertoliDepartment of Biomedical Sciences, University of Padova, 35131 Padova, Italy. alessandro.bertoli@unipd.it.
University of Padua · ITIstituti Clinici Scientifici Maugeri · ITNeuroscience Institute · IT

Funding

AriSLA Foundation LoCaLS 2013University of Padova PRAT CPDA158035/15University of Padova UNIPD funds for research equipment 2015
6 · The paper itself

Abstract

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder characterized by the selective death of motor neurons (MNs), probably by a combination of cell- and non-cell-autonomous processes. The past decades have brought many important insights into the role of astrocytes in nervous system function and disease, including the implication in ALS pathogenesis possibly through the impairment of Ca

Indexed as

Amyotrophic Lateral SclerosisAnimalsAstrocytesCalcium SignalingMice, TransgenicSarcoplasmic Reticulum Calcium-Transporting ATPasesSpinal CordSuperoxide Dismutase-1Sarcoplasmic Reticulum Calcium-Transporting ATPasesSuperoxide Dismutase-1amyotrophic lateral sclerosisastrocytesCa2+ signalingendoplasmic reticulumOraiSERCASTIMstore-operated Ca2+ entrytransgenic mice

Identifiers

PMID31627428
PMCPMC6829245
OpenAlexW2981224400

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.