Evidence map›Paper›PMID 31627408›Full record

ArticleNutrients2019

Greater Circulating Copper Concentrations and Copper/Zinc Ratios are Associated with Lower Psychological Distress, But Not Cognitive Performance, in a Sample of Australian Older Adults.

Michelle Mravunac, Ewa A Szymlek-Gay, Robin M Daly, Blaine R Roberts, Melissa Formica, Jenny Gianoudis, Stella L O'Connell, Caryl A Nowson, Barbara R Cardoso

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 31 citations in OpenAlex.

  1. Mediation effects of thyroid hormones in the associations between essential metal elements and anxiety or depression symptoms in the elderly.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026
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  11. The emerging role of copper in depression.Frontiers in neuroscience · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Michelle MravunacInstitute for Physical Activity and Nutrition (IPAN), School of Exercise and Nutrition Sciences, Deakin University, Geelong, VIC 3220, Australia. michelle.mravunac@eweb.endeavour.edu.au.
Ewa A Szymlek-GayInstitute for Physical Activity and Nutrition (IPAN), School of Exercise and Nutrition Sciences, Deakin University, Geelong, VIC 3220, Australia. ewa.szymlekgay@deakin.edu.au.ORCID 0000-0002-6533-7945
Robin M DalyInstitute for Physical Activity and Nutrition (IPAN), School of Exercise and Nutrition Sciences, Deakin University, Geelong, VIC 3220, Australia. robin.daly@deakin.edu.au.ORCID 0000-0002-9897-1598
Blaine R RobertsMelbourne Dementia Research Centre, The Florey Institute of Neuroscience and Mental Health, Parkville, VIC 3052, Australia. blaine.roberts@florey.edu.au.ORCID 0000-0001-5466-0053
Melissa FormicaInstitute for Physical Activity and Nutrition (IPAN), School of Exercise and Nutrition Sciences, Deakin University, Geelong, VIC 3220, Australia. melissa.prosser@deakin.edu.au.
Jenny GianoudisInstitute for Physical Activity and Nutrition (IPAN), School of Exercise and Nutrition Sciences, Deakin University, Geelong, VIC 3220, Australia. j.gianoudis@deakin.edu.au.ORCID 0000-0002-7022-6377
Stella L O'ConnellInstitute for Physical Activity and Nutrition (IPAN), School of Exercise and Nutrition Sciences, Deakin University, Geelong, VIC 3220, Australia. stella.oconnell@deakin.edu.au.ORCID 0000-0003-4611-4065
Caryl A NowsonInstitute for Physical Activity and Nutrition (IPAN), School of Exercise and Nutrition Sciences, Deakin University, Geelong, VIC 3220, Australia. caryl.nowson@deakin.edu.au.ORCID 0000-0001-6586-7965
Barbara R CardosoInstitute for Physical Activity and Nutrition (IPAN), School of Exercise and Nutrition Sciences, Deakin University, Geelong, VIC 3220, Australia. barbara.cardoso@monash.edu.ORCID 0000-0002-6393-1377
Deakin University · AUFlorey Institute of Neuroscience and Mental Health · AU

Funding

Agilent Technologies NAAlfred Deakin Postdoctoral Research Fellowship NAMeat and Livestock Australia NANHMRC APP1164692NHMRC Dementia Leadership Fellowship APP1138673Victorian Government's Operational Infrastructure Support Program NA
6 · The paper itself

Abstract

Dyshomeostasis of copper and zinc is linked to neurodegeneration. This study investigated the relationship between circulating copper and zinc and copper/zinc ratios and cognitive function, symptoms of depression and anxiety, and neurotrophic factors in older Australian adults. In this cross-sectional study (

Indexed as

Psychological DistressAgedAged, 80 and overAnxietyAustraliaCognitionCopperDepressionFemaleHumansMaleZincCopperZincanxietycognitioncoppercopper/zincdementiadepressionneurotrophic factorszinc

Identifiers

PMID31627408
PMCPMC6836146
OpenAlexW2980980056

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.