ArticleBrain sciences2019
Association of Polygenic Liability for Alcohol Dependence and EEG Connectivity in Adolescence and Young Adulthood.
Article in Brain sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.
- Effects of Alcohol on EEG Activity: A Systematic Review Focused on Sex-Related Differences in Youth.Current neuropharmacology · 2025Pooled it
- Lifespan Trajectories of Resting State EEG power.bioRxiv : the preprint server for biology · 2026Article
- Review
- The effects of polygenic risks for alcohol misuse on negative emotion processing in young adult binge drinkers.Translational psychiatry · 2025Article
- The genetic landscape of substance use disorders.Molecular psychiatry · 2024Review
- Alcohol milestones and internalizing, externalizing, and executive function: longitudinal and polygenic score associations.Psychological medicine · 2024Article
- Associations Between Family History of Alcohol and/or Substance Use Problems and Frontal Cortical Development From 9 to 13 Years of Age: A Longitudinal Analysis of the ABCD Study.Biological psychiatry global open science · 2024Article
- The collaborative study on the genetics of alcoholism: Brain function.Genes, brain, and behavior · 2023Review
- Predicting Alcohol-Related Memory Problems in Older Adults: A Machine Learning Study with Multi-Domain Features.Behavioral sciences (Basel, Switzerland) · 2023Article
- Changes in Electroencephalography Alpha Associated With Childhood Neglect and Adolescent Alcohol Use.Child maltreatment · 2023Article
- Genetic and Brain Mechanisms of Addictive Behavior and Neuroadaptation.Brain sciences · 2021Article
- Reaction Time and Visual Memory in Connection to Hazardous Drinking Polygenic Scores in Schizophrenia, Schizoaffective Disorder and Bipolar Disorder.Brain sciences · 2021Article
- Large-scale collaboration in ENIGMA-EEG: A perspective on the meta-analytic approach to link neurological and psychiatric liability genes to electrophysiological brain activity.Brain and behavior · 2021Article
- The association of polygenic risk for schizophrenia, bipolar disorder, and depression with neural connectivity in adolescents and young adults: examining developmental and sex differences.Translational psychiatry · 2021Article
- Trajectories of brain development reveal times of risk and factors promoting resilience to alcohol use during adolescence.International review of neurobiology · 2021Review
- The Maximum Eigenvalue of the Brain Functional Network Adjacency Matrix: Meaning and Application in Mental Fatigue Evaluation.Brain sciences · 2020Article
Corrections and comments
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Authors and funding
22 authors at 8 institutions in 2 countries.
Funding
Abstract
Differences in the connectivity of large-scale functional brain networks among individuals with alcohol use disorders (AUD), as well as those at risk for AUD, point to dysfunctional neural communication and related cognitive impairments. In this study, we examined how polygenic risk scores (PRS), derived from a recent GWAS of DSM-IV Alcohol Dependence (AD) conducted by the Psychiatric Genomics Consortium, relate to longitudinal measures of interhemispheric and intrahemispheric EEG connectivity (alpha, theta, and beta frequencies) in adolescent and young adult offspring from the Collaborative Study on the Genetics of Alcoholism (COGA) assessed between ages 12 and 31. Our findings indicate that AD PRS (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.