Evidence map›Paper›PMID 31627375›Full record

ArticleNanomaterials (Basel, Switzerland)2019

Silica-Coated Magnetic Nanoparticles Decrease Human Bone Marrow-Derived Mesenchymal Stem Cell Migratory Activity by Reducing Membrane Fluidity and Impairing Focal Adhesion.

Tae Hwan Shin, Da Yeon Lee, Abdurazak Aman Ketebo, Seungah Lee, Balachandran Manavalan, Shaherin Basith, Chanyoung Ahn, Seong Ho Kang, Sungsu Park, Gwang Lee

Open access · goldAbstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 54 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Mechanobiological Analysis of Nanoparticle Toxicity.Nanomaterials (Basel, Switzerland) · 2023
    Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Mesenchymal Stem Cells for Neurological Disorders.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021
    Review
  13. Article
  14. Review
  15. Article
  16. Nanotechnology for Environmental and Biomedical Research.Nanomaterials (Basel, Switzerland) · 2020
    Article
  17. Cell Membrane Coated-Biomimetic Nanoplatforms Toward Cancer Theranostics.Frontiers in bioengineering and biotechnology · 2020
    Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Tae Hwan ShinDepartment of Physiology, Ajou University School of Medicine, Suwon 16499, Korea. catholicon@ajou.ac.kr.ORCID 0000-0001-9686-4556
Da Yeon LeeDepartment of Physiology, Ajou University School of Medicine, Suwon 16499, Korea. ekdus93@ajou.ac.kr.
Abdurazak Aman KeteboSchool of Mechanical Engineering, Sungkyunkwan University, Suwon 16419, Korea. anuabman@gmail.com.
Seungah LeeDepartment of Applied Chemistry and Institute of Natural Sciences, Kyung Hee University, Yongin-si 17104, Korea. moon11311@naver.com.
Balachandran ManavalanDepartment of Physiology, Ajou University School of Medicine, Suwon 16499, Korea. bala.msuman@gmail.com.
Shaherin BasithDepartment of Physiology, Ajou University School of Medicine, Suwon 16499, Korea. shaherinb@gmail.com.
Chanyoung AhnDepartment of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA. justinahn99@berkeley.edu.
Seong Ho KangDepartment of Applied Chemistry and Institute of Natural Sciences, Kyung Hee University, Yongin-si 17104, Korea. shkang@khu.ac.kr.ORCID 0000-0003-2101-4113
Sungsu ParkSchool of Mechanical Engineering, Sungkyunkwan University, Suwon 16419, Korea. nanopark@skku.edu.ORCID 0000-0003-3062-1302
Gwang LeeDepartment of Physiology, Ajou University School of Medicine, Suwon 16499, Korea. glee@ajou.ac.kr.
Ajou University · KRKyung Hee University · KRSungkyunkwan University · KRUniversity of California, Berkeley · US

Funding

The National Research Foundation (NRF) by Korea goverment 2018R1D1A1B07049494
6 · The paper itself

Abstract

For stem cell-based therapies, the fate and distribution of stem cells should be traced using non-invasive or histological methods and a nanomaterial-based labelling agent. However, evaluation of the biophysical effects and related biological functions of nanomaterials in stem cells remains challenging. Here, we aimed to investigate the biophysical effects of nanomaterials on stem cells, including those on membrane fluidity, using total internal reflection fluorescence microscopy, and traction force, using micropillars of human bone marrow-derived mesenchymal stem cells (hBM-MSCs) labelled with silica-coated magnetic nanoparticles incorporating rhodamine B isothiocyanate (MNPs@SiO

Indexed as

cytoskeletal abnormalityfocal adhesionhuman bone marrow-derived mesenchymal stem cellsmagnetic nanoparticlesmembrane fluidity

Identifiers

PMID31627375
PMCPMC6835988
OpenAlexW2981147377

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.