Evidence map›Paper›PMID 31627345›Full record

ArticleViruses2019

Environmental Contamination and Hygienic Measures After Feline Calicivirus Field Strain Infections of Cats in a Research Facility.

Andrea Monika Spiri, Marina Luisa Meli, Barbara Riond, Imogen Herbert, Margaret J Hosie, Regina Hofmann-Lehmann

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Andrea Monika SpiriClinical Laboratory, Department of Clinical Diagnostics and Services, and Center for Clinical Studies, Vetsuisse Faculty, University of Zurich, 8057 Zurich, Switzerland. aspiri@vetclinics.uzh.ch.ORCID 0000-0001-9009-8256
Marina Luisa MeliClinical Laboratory, Department of Clinical Diagnostics and Services, and Center for Clinical Studies, Vetsuisse Faculty, University of Zurich, 8057 Zurich, Switzerland. mmeli@vetclinics.uzh.ch.ORCID 0000-0002-3609-2416
Barbara RiondClinical Laboratory, Department of Clinical Diagnostics and Services, and Center for Clinical Studies, Vetsuisse Faculty, University of Zurich, 8057 Zurich, Switzerland. briond@vetclinics.uzh.ch.
Imogen HerbertMedical Research Council, University of Glasgow Centre for Virus Research, Glasgow G61 1QH, UK. i.herbert.1@research.gla.ac.uk.
Margaret J HosieMedical Research Council, University of Glasgow Centre for Virus Research, Glasgow G61 1QH, UK. Margaret.Hosie@glasgow.ac.uk.ORCID 0000-0002-4313-5023
Regina Hofmann-LehmannClinical Laboratory, Department of Clinical Diagnostics and Services, and Center for Clinical Studies, Vetsuisse Faculty, University of Zurich, 8057 Zurich, Switzerland. rhofmann@vetclinics.uzh.ch.ORCID 0000-0001-9750-4296
University of Zurich · CHMRC University of Glasgow Centre for Virus Research · GB

Funding

Biotechnology and Biological Sciences Research Council BB/D008425/1Medical Research Council G0300387
6 · The paper itself

Abstract

Feline calicivirus (FCV) can cause painful oral ulcerations, salivation, gingivitis/stomatitis, fever and depression in infected cats; highly virulent virus variants can lead to fatal epizootic outbreaks. Viral transmission occurs directly or indirectly via fomites. The aim of this study was to investigate the presence and viability of FCV in the environment after sequential oronasal infections of specified pathogen-free cats with two FCV field strains in a research facility. Replicating virus was detected in saliva swabs from all ten cats after the first and in four out of ten cats after the second FCV exposure using virus isolation to identify FCV shedders. In the environment, where cleaning, but no disinfection took place, FCV viral RNA was detectable using RT-qPCR on all tested items and surfaces, including cat hair. However, only very limited evidence was found of replicating virus using virus isolation. Viral RNA remained demonstrable for at least 28 days after shedding had ceased in all cats. Disinfection with 5% sodium bicarbonate (and Incidin

Indexed as

Equipment ContaminationMicrobial ViabilityAnimalsAntibodies, ViralCaliciviridae InfectionsCalicivirus, FelineCat DiseasesCatsDisease OutbreaksDisinfectionEnvironmental MicrobiologyLaboratoriesMaleRNA, ViralAntibodies, ViralRNA, Viralcatsdisinfectionenvironmental testingfeline calicivirushygienic measuresRT-qPCRsheddingsodium bicarbonateveterinary sciencesvirus isolationvirus survival

Identifiers

PMID31627345
PMCPMC6832521
OpenAlexW2980942395

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.