Evidence map›Paper›PMID 31627077›Full record

ArticleDrug and alcohol dependence2019

Suicidal motivations reported by opioid overdose survivors: A cross-sectional study of adults with opioid use disorder.

Hilary S Connery, Nadine Taghian, Jungjin Kim, Margaret Griffin, Ian R H Rockett, Roger D Weiss, R Kathryn McHugh

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Drug and alcohol dependence, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 1 pooled it
9.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 1 synthesis or guideline pooled it, 79 citations in OpenAlex.

  1. Mental disorder and opioid overdose: a systematic review.Social psychiatry and psychiatric epidemiology · 2022
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  18. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Hilary S ConneryMcLean Hospital, 115 Mill Street, Belmont, MA 02478, USA; Harvard Medical School, Departments of Psychiatry/Psychology, 25 Shattuck Street, Boston, MA 02115, USA. Electronic address: hconnery@mclean.harvard.edu.
Nadine TaghianMcLean Hospital, 115 Mill Street, Belmont, MA 02478, USA. Electronic address: ntaghian@partners.org.
Jungjin KimMcLean Hospital, 115 Mill Street, Belmont, MA 02478, USA; Partners Health Care Addiction Psychiatry Fellowship Training Program, 115 Mill Street, Belmont, MA 02478, USA. Electronic address: jungjin.kim.md@gmail.com.
Margaret GriffinMcLean Hospital, 115 Mill Street, Belmont, MA 02478, USA; Harvard Medical School, Departments of Psychiatry/Psychology, 25 Shattuck Street, Boston, MA 02115, USA. Electronic address: mgriffin@mclean.harvard.edu.
Ian R H RockettWest Virginia University, Department of Epidemiology, One Waterfront Place, Morgantown, WV 26506-6009, USA; University of Rochester Medical Center, Department of Psychiatry, 601 Elmwood Avenue, Rochester, NY 14642, USA. Electronic address: irockett@hsc.wvu.edu.
Roger D WeissMcLean Hospital, 115 Mill Street, Belmont, MA 02478, USA; Harvard Medical School, Departments of Psychiatry/Psychology, 25 Shattuck Street, Boston, MA 02115, USA. Electronic address: rweiss@mclean.harvard.edu.
R Kathryn McHughMcLean Hospital, 115 Mill Street, Belmont, MA 02478, USA; Harvard Medical School, Departments of Psychiatry/Psychology, 25 Shattuck Street, Boston, MA 02115, USA. Electronic address: kmchugh@mclean.harvard.edu.
Harvard University · USMcLean Hospital · USWest Virginia University · US

Funding

The National Drug Abuse Treatment Clinical Trials NetworkUG1DA015831 · NIDA · YALE UNIVERSITY · PI Gail D'Onofrio, Roger D. Weiss · 2015 to 2026
$110.8M
Mentoring in Drug Abuse and Dual Diagnosis ResearchK24DA022288 · NIDA · MCLEAN HOSPITAL · PI WEISS, ROGER D. · 2007 to 2016
$1.8M
GENDER DIFFERENCES IN MECHANISMS OF RECOVERY FROM OPIOID USE DISORDER AND ANXIETYK23DA035297 · NIDA · MCLEAN HOSPITAL · PI MCHUGH, REBECCA KATHRYN · 2014 to 2018
$959k
Implicit and Explicit Suicidal Cognition and Risk for Opioid OverdoseR21DA046521 · NIDA · MCLEAN HOSPITAL · PI MCHUGH, REBECCA KATHRYN · 2019 to 2020
$451k
NIDA NIH HHS K23 DA035297NIDA NIH HHS K24 DA022288NIDA NIH HHS R21 DA046521NIDA NIH HHS UG1 DA015831
6 · The paper itself

Abstract

backgroundPrior studies in heroin use disorder reported low rates (10%) of suicidal intention with non-fatal opioid overdose but did not assess dimensional ratings of suicidal ideation. This study aims to quantify the frequency and intensity of ratings of desire to die and perceived overdose risk proximal to the most recent opioid overdose event among individuals admitted for opioid use disorder detoxification/stabilization.

methodsCross-sectional study (June 2017-July 2018) assessing patterns of opioid use and variables related to overdose history was conducted in a not-for-profit psychiatric hospital. Adults (>18 years) with opioid use disorder were eligible and 120 of 122 participants completed all measures. Forty-one percent were women and 85% self-identified as white. Participants' perceptions of the likelihood of overdose and their suicidal motivations (defined as desire to die) prior to most recent opioid overdose was self-rated on a scale of 0 (no desire to die/no risk of death) to 10 (I definitely wanted to die/I definitely thought I would die).

resultsMost (92%) surviving opioid overdose used heroin/fentanyl; over half reported some desire to die prior to their most recent overdose, with 36% reporting strong (>7/10) desire to die and 21% reporting 10/10 "I definitely wanted to die." Perceptions of overdose risk were also variable, with 30% reporting no (0/10) likelihood of overdose and 13% reporting a high (10/10) likelihood.

conclusionsSuicidal motivation prior to opioid overdose is common and falls along a continuum of severity. Longitudinal studies are needed to determine if suicide prevention interventions may reduce opioid overdose in those at risk.

Indexed as

MotivationSuicidal IdeationAdultCross-Sectional StudiesDrug OverdoseFemaleFentanylHeroinHospitalizationHumansLongitudinal StudiesMaleMiddle AgedOpioid-Related DisordersSelf ReportSurvivorsFentanylHeroinOpioid overdoseOpioid use disorderOverdose preventionSuicidal motivationSuicide

Identifiers

PMID31627077
PMCPMC6929689
OpenAlexW2978797627

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.