Evidence map›Paper›PMID 31626546›Full record

ArticleThe Journal of organic chemistry2019

Synthesis of 5-(Fluoroalkyl)isoxazole Building Blocks by Regioselective Reactions of Functionalized Halogenoximes.

Bohdan A Chalyk, Kateryna V Hrebeniuk, Yulia V Fil, Konstantin S Gavrilenko, Alexander B Rozhenko, Bohdan V Vashchenko, Oleksandr V Borysov, Angelina V Biitseva, Pavlo S Lebed, Iulia Bakanovych and 2 more

Abstract read
In one paragraph

Article in The Journal of organic chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Copper-Catalyzed Synthesis of 4-CFMolecules (Basel, Switzerland) · 2024
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Bohdan A ChalykEnamine Ltd , (www.enamine.net), Chervonotkatska Street 78 , Kyiv 02094 , Ukraine.
Kateryna V HrebeniukEnamine Ltd , (www.enamine.net), Chervonotkatska Street 78 , Kyiv 02094 , Ukraine.
Yulia V FilEnamine Ltd , (www.enamine.net), Chervonotkatska Street 78 , Kyiv 02094 , Ukraine.
Konstantin S GavrilenkoEnamine Ltd , (www.enamine.net), Chervonotkatska Street 78 , Kyiv 02094 , Ukraine.
Alexander B RozhenkoInstitute of Organic Chemistry , National Academy of Sciences of Ukraine , Murmanska Street 5 , Kyiv 02660 , Ukraine.
Bohdan V VashchenkoEnamine Ltd , (www.enamine.net), Chervonotkatska Street 78 , Kyiv 02094 , Ukraine.
Oleksandr V BorysovEnamine Ltd , (www.enamine.net), Chervonotkatska Street 78 , Kyiv 02094 , Ukraine.
Angelina V BiitsevaEnamine Ltd , (www.enamine.net), Chervonotkatska Street 78 , Kyiv 02094 , Ukraine.
Pavlo S LebedEnamine Ltd , (www.enamine.net), Chervonotkatska Street 78 , Kyiv 02094 , Ukraine.
Iulia BakanovychEnamine Ltd , (www.enamine.net), Chervonotkatska Street 78 , Kyiv 02094 , Ukraine.
Yurii S MorozEnamine Ltd , (www.enamine.net), Chervonotkatska Street 78 , Kyiv 02094 , Ukraine.
Oleksandr O GrygorenkoEnamine Ltd , (www.enamine.net), Chervonotkatska Street 78 , Kyiv 02094 , Ukraine.ORCID 0000-0002-6036-5859

Funding

Ultra-large library docking for ligand discoveryR01GM133836 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI IRWIN, JOHN J. · 2019 to 2022
$1.6M
NIGMS NIH HHS R01 GM133836
6 · The paper itself

Abstract

A comprehensive study on the synthesis of 5-fluoroalkyl-substituted isoxazoles starting from functionalized halogenoximes is reported. One-pot metal-free [3 + 2] cycloaddition of CF

Indexed as

CyclizationIsoxazolesMolecular StructureOximesStereoisomerismIsoxazolesOximes

Identifiers

PMID31626546
PMCPMC7341682

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.