ArticleInternational braz j urol : official journal of the Brazilian Society of Urology
Improvement of fertility parameters with Tribulus Terrestris and Anacyclus Pyrethrum treatment in male rats.
Article in International braz j urol : official journal of the Brazilian Society of Urology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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11 citing papers in PubMed, 46 citations in OpenAlex.
- Polyherbal Therapeutics Mitigate CClReproductive sciences (Thousand Oaks, Calif.) · 2025Article
- Agro-morphological characterization and assessment of metabolic profiling and anticancer activities in various tribulus (Tribulus terrestris L.) populations.BMC plant biology · 2025Article
- Evaluation of Selected Folk Herbs on the Fertility of Sprague Dawley Male Rats: Biochemical, Histological, and Molecular Investigations.Life (Basel, Switzerland) · 2024Article
- Anacyclus pyrethrum enhances fertility in cadmium-intoxicated male rats by improving sperm functions.BMC complementary medicine and therapies · 2024Article
- Promising phytopharmacology, nutritional potential, health benefits, and traditional usage ofHeliyon · 2024Review
- Effects of Vincamine on Testicular Dysfunction in Alloxan-induced Diabetic Male Rats.Iranian journal of pharmaceutical research : IJPR · 2022Article
- Puncture vine (Tribulus Terrestris L.) in control of health and reproduction.Physiological research · 2021Review
- Successful transplantation of spermatogonial stem cells into the seminiferous tubules of busulfan-treated mice.Reproductive health · 2021Article
- Article
- A Comprehensive Review of the Phytochemical, Pharmacological, and Toxicological Properties ofBiomolecules · 2020Review
- Editorial Comment: Improvement of fertility parameters with Tribulus Terrestris and Anacyclus Pyrethrum treatment in male rats.International braz j urol : official journal of the Brazilian Society of UrologyArticle
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8 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
objectiveAnacyclus Pyrethrum (AP) and Tribulus Terrestris (TT) have been reported as male infertility treatment in several studies; however, in Iranian traditional medicine these two plants are prescribed simultaneously. In this study, we aimed to determine the effects of AP and TT extracts both separately and simultaneously on the male Wistar rat fertility parameters. MATERIALS AND
methods32 male Wistar rats were divided into 4 groups: Control, TT, AP, and AT treated groups. Treatment continued for 25 days and rats were weighed daily. Their testes were dissected for histological studies. Sperm analysis including sperm count, viability and motility were performed. Serum was obtained to evaluate testosterone, LH and FSH levels. Histological studies were conducted to study Leydig, and Sertoli cells, spermatogonia and spermatid cell numbers, and to measure seminiferous diameter and epithelium thickness.
resultsSperm count increased in all the treatment groups. Sperm viability and motility in AT and AP groups were elevated. TT and AT groups showed signifi cantly increased testosterone level compared to control group (P=004, P=0.000, respectively) and TT, AP and AT treatment groups showed increased LH level (P=0.002, P=0.03 and P=0.000, respectively) compared to control, while only AT group showed increased FSH (p=0.006) compared to control. Histological studies showed signifi cant increase of spermatogonia, Leydig and Sertoli cell numbers and epithelial thickness in AT group compared to other groups. All the treatment groups had higher number of Leydig, spermatogonia and spermatid cells.
conclusionTT and AP improved sexual parameters; however, their simultaneous administration had higher improving effects on studied parameters.
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