SynthesisMedicine2019
Poststroke depression and risk of recurrent stroke: A meta-analysis of prospective studies.
Synthesis in Medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 6 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
43 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Exercise-based interventions for post-stroke depression: an overview of systematic reviews and evidence mapping.Frontiers in neurology · 2026Pooled it
- Depression and health outcomes: An umbrella review of systematic reviews and meta-analyses of observational studies.Translational psychiatry · 2025Pooled it
- Exploring the occurence and risk factors of post-stroke depression among stroke survivors in Africa: a comprehensive systematic review and meta-analysis.BMC public health · 2025Pooled it
- The Role of Spirituality in Stroke Survivors and Their Caregivers: A Systematic Review.Journal of religion and health · 2024Pooled it
- Prevalence and natural history of depression after stroke: A systematic review and meta-analysis of observational studies.PLoS medicine · 2023Pooled it
- Effects of noninvasive brain stimulation in the treatment of poststroke depression: an overview of systematic reviews.Frontiers in neurologyPooled it
- Efficacy of Daoyin combined with lower limb robot as a comprehensive rehabilitation intervention for stroke patients: a randomized controlled trial.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan · 2024Trial
- Health risk factors in Australian Stroke Survivors: A latent class analysis.Health promotion journal of Australia : official journal of Australian Association of Health Promotion Professionals · 2024Trial
- Access to and Use of Internet and Social Media by Low-Morbidity Stroke Survivors Participating in a National Web-Based Secondary Stroke Prevention Trial: Cross-sectional Survey.Journal of medical Internet research · 2022Trial
- Depressive Symptoms After Mechanical Thrombectomy in Ischaemic Stroke: A Longitudinal Descriptive Study with Gender Differences.Healthcare (Basel, Switzerland) · 2026Article
- Knowledge, attitude, and practice toward post-stroke depression among stroke caregivers: a cross-sectional study and path analysis.BMC neurology · 2026Article
- Predictors of post-stroke depression and anxiety at three months following acute ischemic stroke.BMC psychiatry · 2026Article
- Review
- Factors associated with antidepressant use following hospitalization for acute stroke.International journal of psychiatry in medicine · 2026Article
- Poststroke anxiety and depression: epidemiology, mechanisms, and management strategies.Frontiers in psychiatry · 2026Review
- The morphometric features derived as the predictors of acute ischemic stroke recurrence.Frontiers in neuroscience · 2026Article
- Leveraging multigenerational health data to enhance mental disorder risk prediction: a population-based cohort study.BMC psychiatry · 2025Article
- Assessing the effects of antidepressant use on stroke recurrence and related outcomes in ischemic stroke patients: a propensity score matched analysis.Frontiers in pharmacology · 2025Article
- Opinions of physiotherapists at the University Teaching Hospital on assessing the psychological well-being of patients with stroke: A qualitative study.PLOS mental health · 2025Article
- Latent profile analysis of depression and anxiety comorbidity in patients with acute ischemic stroke: a prospective study.Frontiers in psychiatry · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundConflicting results have been reported on the association of poststroke depression with recurrent stroke events. This meta-analysis of prospective studies aims to evaluate whether poststroke depression is an independent predictor of stroke recurrence among stroke patients.
methodsA systematic search of articles in PubMed and Embase databases from their inception to October 2018 was conducted. Prospective studies reporting risk estimates of stroke recurrence by depression status in stroke patients were included and pooled risk ratio (RR) with 95% confidence intervals (CIs) of stroke recurrence was calculated for patients with or without poststroke depression.
resultsSix studies with 4648 stroke patients were finally included, and the prevalence of poststroke depression was found to from 15.9% to 40.5%. The pooled adjusted RR for stroke recurrence in patients suffering from poststroke depression was 1.48 (1.22-1.79) in a fixed-effect model. Subgroup analyses indicated that poststroke depression significantly increased stroke recurrence (RR 1.64; 95% CI, 1.28-2.10) among ischemic stroke patients but not in total stroke patients (RR 1.28; 95% CI, 0.96-1.73).
conclusionsThis meta-analysis suggests that poststroke depression may be an independent predictor of stroke recurrence among ischemic stroke patients. Further studies are required to investigate whether treatment of poststroke depression can reduce the risk of stroke recurrence.
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