ArticleThe Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology2019
Impaired thiol/disulfide homeostasis in patients with mild acute pancreatitis.
Article in The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- An evaluation of maternal serum dynamic thiol-disulfide homeostasis and ischemia modified albumin changes in pregnant women with COVID-19.Turkish journal of obstetrics and gynecology · 2022Article
- Evaluation of the Paraoxonase-1 Level in Patients with Acute Pancreatitis.Current health sciences journalArticle
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Authors and funding
6 authors.
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Abstract
BACKGROUND/
aimsThe aim of this study was to compare the dynamic thiol/disulfide (SS) homeostasis and ischemia-modified albumin (IMA) concentration between healthy subjects and patients with mild acute pancreatitis (AP). MATERIALS AND
methodsA total of 28 patients with AP (AP group) and 35 age- and sex-matched healthy individuals (control group) were included in this study. Serum thiols/SS and IMA concentrations were measured and compared between the two groups.
resultsThe mean serum native thiol (SH) and total thiol (TT) levels were significantly lower in the AP group than in the control group (224.7±80.3 μmol/L vs. 314.66±87.5 μmol/L, p<0.001 and 273.3±76.8 vs. 346.9±79 μmol/L, p<0.001, respectively). SS levels were significantly higher in the AP group than in the control group (24.2±11.1 μmol/L vs. 16.1±9.9 μmol/L, p<0.054). There were no differences in the IMA concentration and the mean IMA/albumin ratio (IMAR) between both the groups.
conclusionWe found that mild AP may affect serum thiol and SS levels, and cause impaired thiol/SS homeostasis.
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