Evidence map›Paper›PMID 31625806›Full record

ArticleHuman vaccines & immunotherapeutics2020

Influenza vaccine and cardiac protection: a study from a tertiary care center.

Umayya Musharrafieh, Jad Dergham, Carla Daou, Hani Tamim, Rana Houry, Abdul Rahman Bizri

Open access · bronzeAbstract read
In one paragraph

Article in Human vaccines & immunotherapeutics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Umayya MusharrafiehDepartment of Family Medicine, American University of Beirut Medical Center, Beirut, Lebanon.
Jad DerghamDepartment of Family Medicine, American University of Beirut Medical Center, Beirut, Lebanon.
Carla DaouDepartment of Family Medicine, American University of Beirut Medical Center, Beirut, Lebanon.
Hani TamimDepartment of Internal Medicine, Division of infectious diseases, American University of Beirut Medical Center, Beirut, Lebanon.ORCID 0000-0002-2019-4362
Rana HouryEcole Normale Supérieure de Lyon, Lyon, France.ORCID 0000-0003-2847-4163
Abdul Rahman BizriDepartment of Internal Medicine, Division of infectious diseases, American University of Beirut Medical Center, Beirut, Lebanon.
American University of Beirut Medical Center · LBÉcole Normale Supérieure de Lyon · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients with heart disease (HD) are at increased risk of developing cardiac complications if they acquire the influenza virus. The objective of this study was to determine whether the influenza vaccine has a primary role in preventing newly diagnosed HD in patients who have no history of HD and who were being followed up at the American University of Beirut Medical Center (AUBMC). The study is a retrospective cohort, with 2-years follow up, which was conducted using electronic medical records between the years of 2011-2013 in a tertiary care center. All patients 60 years and older (n = 698) who have taken the flu vaccine were randomly selected from the University Health Service records (UHS) and compared to a group who has not taken the flu vaccine during the same period. The odds of developing HD among vaccinated people with cofactors are 0.97 times the odds of that among non-vaccinated. This odds ratio is not significantly different than that of people vaccinated without cofactors (OR = 1.74). The occurrence of HD in the presence of vaccination revealed a non-significant decrease trend with the increase in a number of risk factors (OR = 1.61 vs 0.97). Our results suggest that there was a non-significant difference between the effect of the vaccine for influenza on patients who had cofactors for HD and those who had not. Similarly, the effect of vaccine showed a non-significant increase in protective effect as the number of comorbidities increase. The potential effects of the vaccine may be related to the protection against flu.

Indexed as

Influenza, HumanInfluenza VaccinesHumansRetrospective StudiesTertiary Care CentersVaccinationInfluenza Vaccineselderlyheart diseaseInfluenza viruspreventionrisk factorsvaccine

Identifiers

PMID31625806
PMCPMC7227676
OpenAlexW2981196035

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.