Evidence map›Paper›PMID 31625414›Full record

ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2019

Methylation-dependent transcriptional repression of RUNX3 by KCNQ1OT1 regulates mouse cardiac microvascular endothelial cell viability and inflammatory response following myocardial infarction.

Yanbin Wang, Xudong Yang, An Jiang, Wei Wang, Jian Li, Junmin Wen

RetractedOpen access · greenAbstract readRetracted Publication
In one paragraph

Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 50 citations in OpenAlex.

  1. Review
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  9. Plumbing mysterious RNAs in "dark genome" for the conquest of human diseases.Molecular therapy : the journal of the American Society of Gene Therapy · 2023
    Review
  10. Article
  11. Expression levels ofAnnals of surgical treatment and research · 2023
    Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. LncRNA-mediated DNA methylation: an emerging mechanism in cancer and beyond.Journal of experimental & clinical cancer research : CR · 2022
    Review
  18. Signaling pathways and targeted therapy for myocardial infarction.Signal transduction and targeted therapy · 2022
    Review
  19. Epigenetic Changes and Functions in Pneumoconiosis.Oxidative medicine and cellular longevity · 2022
    Review
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Yanbin WangDepartment of Anesthesia, Chinese Academy of Medical Sciences, Shenzhen, China.
Xudong YangDepartment of Biochemistry and Molecular Biology, School of Medicine, Xi'an, China.
An JiangGeneral Surgeon Department of Cadre's Ward, The Second Affiliated Hospital, Xi'an Jiaotong University, Xi'an, China.
Wei WangDepartment of Anesthesia, Chinese Academy of Medical Sciences, Shenzhen, China.
Jian LiDepartment of Anesthesia, Chinese Academy of Medical Sciences, Shenzhen, China.
Junmin WenDepartment of Intensive Care Medicine, Fuwai Hospital, Chinese Academy of Medical Sciences, Shenzhen, China.
Chinese Academy of Medical Sciences & Peking Union Medical College · CNSecond Affiliated Hospital of Xi'an Jiaotong University · CNXi’an University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myocardial infarction (MI) is a major contributor to death and disability throughout the world. Increasing evidence shows that long noncoding RNAs (lncRNAs) are involved in the progression of MI. Here, we hypothesized that lncRNA potassium voltage-gated channel subfamily q member 1 overlapping transcript 1 (KCNQ1OT1) could affect the development of MI

Indexed as

AnimalsCell SurvivalChromatin ImmunoprecipitationCore Binding Factor Alpha 3 SubunitDNA (Cytosine-5-)-Methyltransferase 1ImmunoprecipitationInflammationIn Situ Nick-End LabelingMaleMiceMice, Inbred C57BLMyocardial InfarctionPotassium Channels, Voltage-GatedCore Binding Factor Alpha 3 SubunitDNA (Cytosine-5-)-Methyltransferase 1Dnmt1 protein, mousePotassium Channels, Voltage-GatedRunx3 protein, mouseCMECsDNMT1MI

Identifiers

PMID31625414
PMCPMC6894069
OpenAlexW2980339510

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.