Evidence map›Paper›PMID 31625323›Full record

ArticleJournal of biomedical optics2019

Evaluation of silicon photomultipliers for multiphoton and laser scanning microscopy.

Michael G Giacomelli

Abstract read
In one paragraph

Article in Journal of biomedical optics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Michael G GiacomelliUniversity of Rochester, Department of Biomedical Engineering, Rochester, New York, United States.

Funding

Fluorescence microscopy for evaluation of Mohs surgical marginsK22CA226035 · NCI · UNIVERSITY OF ROCHESTER · PI GIACOMELLI, MICHAEL GENE · 2019 to 2021
$559k
NCI NIH HHS K22 CA226035
6 · The paper itself

Abstract

The silicon photomultiplier (SIPM) is an emerging detector technology that enables both high sensitivity and high dynamic range detection of visible and near-infrared light at a fraction of the cost of conventional vacuum tube photomultiplier tubes (PMTs). A low-cost detection circuit is presented and the performance of a commercial SIPM is evaluated for high-speed laser scanning microscopy applications. For moderate-to-high-speed fluorescent imaging applications, the measurements and imaging results indicate that the SIPM exceeds the sensitivity of GaAsP PMTs, while providing higher dynamic range and better saturation behavior. For low speed or applications requiring large detector areas, the GaAsP PMT retains a sensitivity advantage due to large area and lower dark counts. The calculations presented show that, above a critical detection bandwidth, the SIPM sensitivity exceeds that of a GaAsP PMT.

Indexed as

Equipment DesignHumansMicroscopy, ConfocalMicroscopy, Fluorescence, MultiphotonPhotonsSignal Processing, Computer-AssistedSignal-To-Noise RatioSiliconSkinSiliconfluorescencemultiphoton microscopysilicon photomultipliersurgical imaging

Identifiers

PMID31625323
PMCPMC7000887

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.